The effect of electroacupuncture in the prevention of chemotherapy induced peripheral neuropathy in colon cancer patient - pilot study
- Conditions
- Neoplasms
- Registration Number
- KCT0001349
- Lead Sponsor
- Daegu Catholic Univercity Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 20
1. proven colorectal cancer patient
2. age between 18 - 75 yrs
3. Patients who receive FOLFOX chemotherapy including Oxaliplatin
4 less than Eastern Cooperative Oncology Group (ECOG) performance status 2
5. patient who is possible to follow up
1. current metastatic colorectal cancer
2. patients who had the experience of being treated due to peripheral neuropathy previously
3. previously being treated with neurotoxic chemotherapeutic agents
4. patients who need operation due to neurologic symptoms
5. prenant, breastfeeding woman
6. patients who have psychological diseases or problems
7. patients who do not agree with the trial
8. Diabetes, chronic renal failure, alcoholics and other addictive patients
9. patients who have anticonvulsants, antidepressant and major painkiller periodically
10. moderate to severe hepatotoxicity or renal toxicity
11. allergic or hyper-reactive response to acupunture
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method CTCAE(Common Terminology Criteria for Adverse Effect) grading system, OSNS(Oxaliplatin-Specific Neurotoxicity Scale),(VAS, EORTC(QLQ-CIPN20) Questionaire)
- Secondary Outcome Measures
Name Time Method CV(Nerve Conduction Velocity), CMAP(compound motor action potential), CSAP(compound sensory action potential)