The cortical excitatory response by monophasic pulse waveform electroacupuncture predicts potential on the upper extremity recovery in patients with acute stroke
- Conditions
- stroke
- Registration Number
- ITMCTR2000003361
- Lead Sponsor
- Yueyang Hospital of Integrated Traditional Chinese and Western Medicine affiliated to Shanghai University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
(1) Patients meet the diagnostic criteria of cerebral infarction with integrated Chinese and western medicine;
(2) Patients diagnosed with cerebral infarction with upper limb movement dysfunction by MRI or CT;
(3) Patients aged 30 to 80 years old male and female;
(4) No limitation on the degree of limb dysfunction within 1 week after the first onset of disease course;
(5) Clear consciousness without obvious aphasia or cognitive dysfunction;
(6) No limb deformity, motor dysfunction or sensory dysfunction before onset;
(7) Without skull defect or other physical diseases, and can withstand the detection for 1h;
(8) Sign informed consent.
(1) Patients with subarachnoid hemorrhage, cerebral embolism, lacunar cerebral infarction and cerebral trauma, who have serious systemic diseases such as cardiopulmonary diseases and cannot tolerate rehabilitation treatment;
(2) Patients with more than two or more cerebral infarction, or with cognitive, verbal, psychological, mental, visual and auditory disorders;
(3) Contraindication of transcranial magnetic stimulation (TMS) and magnetic resonance (MRI) examination, such as pacemaker, metal implant, etc., in pregnant or lactating women;
(4) Patients with motor dysfunction before onset should apply drugs (antiepileptic drugs, sedative and hypnotic drugs, etc.) to change the excitability of cerebral cortex;
(5) Pregnant or lactating women.
Study & Design
- Study Type
- Diagnostic test
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 120%resting motor threshold ;short-interval intracortical inhibition;Fugl-Meyer motor assessment of the upper extremity;short-interval intracortical inhibition;motor evoked potential (MEP);
- Secondary Outcome Measures
Name Time Method shoulder abduction and finger extension;The National Institutes of Health Stroke Scale;