Seroprevalence of Hepatitis B and Immune Response to Hepatitis B Vaccination in Chinese College Students
Phase 4
Completed
- Conditions
- Immune ResponseSeroprevalenceHepatitis B
- Registration Number
- NCT01861613
- Lead Sponsor
- Hui Zhuang
- Brief Summary
At present, children less than 15 y of age have been regarded as a key group for hepatitis B immunization in China. However, there is not yet special immunization strategy for population above 15 y of age. In this study, we investigated the seroprevalence of hepatitis B and immune response to HB vaccine among Chinese college students to uncover the need on universal mass vaccination or booster immunization only for students with HBV vaccination history against hepatitis B in Chinese college students to inform decision making.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 2040
Inclusion Criteria
- Male and female freshmen in one college in Liuzhou city of Guangxi Zhuang Autonomous Region
Exclusion Criteria for vaccination study:
- acute illness
- immunocompromised conditions
- renal insufficiency
- pregnancy
- allergic history to HB vaccine or yeast
- positive for any of HBsAg, anti-HBs or anti-HBc
Exclusion Criteria
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Anti-HBs immune response in participants negative for HB sAg, anti-HBs and anti-HBc Anti-HBs was assayed at Month 7
- Secondary Outcome Measures
Name Time Method Seroprevalence for HBsAg, anti-HBs and anti-HBc in Chinese college students seroprevalence at baseline Anti-HBs immune response in participants negative for HBsAg, anti-HBs and anti-HBc Anti-HBs immune response at Month 20
Trial Locations
- Locations (1)
Guangxi Centers for Disease Control and Prevention
🇨🇳Nanning, Guangxi, China
Guangxi Centers for Disease Control and Prevention🇨🇳Nanning, Guangxi, China