To evaluate the efficacy of Vamana with Madhanaphala Dadhiyoga and Madhanaphala Yoga of Vamana in Tamaka Swasa vis-a-vis to Bronchial Asthma
- Conditions
- Mild intermittent asthma. Ayurveda Condition: TAMAKASVASAH, (2) ICD-10 Condition: J453||Mild persistent asthma. Ayurveda Condition: TAMAKASVASAH, (3) ICD-10 Condition: J454||Moderate persistent asthma. Ayurveda Condition: TAMAKASVASAH,
- Registration Number
- CTRI/2023/09/057211
- Lead Sponsor
- Dr. Niti Y. Laheru
- Brief Summary
Arandomised open labelled comparative clinical study to evaluate the efficacy of*Vamana* with *Madhanaphala Dadhiyoga* and *Madhanaphala Yoga ofVamana* in *Tamaka Swasa* vis-a-vis to Bronchial Asthma.
P GScholar : Dr. Niti Laheru Guide : Prof. Prajwal Narayan
Introduction:*Tamaka Swasa*,one among the 5 types of *Swasa Roga*. it is analogous with BronchialAsthma having cardinal features of episodic attacks of breathlessness,tightness in the chest, wheezing, coughing and increased mucus production.Asthma attacks can begin suddenly and range from mild to life threatening as itmay lead to swelling in the airways which prevents oxygen to reach the lungsand hence urgent medical attention becomes necessary. According to WHO report,100-150 million of global populations are suffering from Bronchial Asthma, outof which 1/10th are Indians and the prevalence of Asthma is increasing everywhereCurrent estimates suggest that 339 million people worldwide suffer from Asthmaand an additional 100 million may be diagnosed with Asthma by 2025. Also by theyear 2020 Asthma along with Chronic Obstructive Pulmonary Disease will becomethe third leading cause of death. *Acharya Charaka* has mentioned that *TamakaSwasa* is *Kapha Vataja - Vikara* and site of origin is *Pittasthana*.Other *Acharyas* have mentioned it as *Kapha Pradhana Vyadhi*. Acritical review of relevant literature about, *Tamaka Swasa* will be doneon the basis of available Ayurvedic text books, previous research works,Journals etc. Clinical study will be carried out in the form of detailedhistory and assessment of the treatment by preparing a specialperformance.
Material and Methods: Total 30 patients of *TamakaSwasa* will be enrolled in this study. Which will be divided in two groups.Group A (Trail group) will be treated with *Madhanaphala Dadhiyoga*. GroupB will be treated with *Madhanaphala yoga* as a standard control. Theraw drugs and prepared product will be subjected to the standardanalytical study protocol followed in the the institute for authencity of rawdrugs and finished product. The duration of treatment will be of 16 daysfollowed by the seven days follow-up. The treatment will also include deatailsof *Pathya- Apathya* (Do’s and Don’ts of diet and regime). Subjectivecriteria will be used in current study for assessment purpose.
Results and Discussion :The assessmentof the treatment will be done based on clinical subsidence in the symptoms interms of percentage and result will be categorized into Complete remission,markedly improved, moderately improved, mild improved and unchanged. Resultswill also be statistically analysed for the purpose of comparison of results ofboth the groups.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 30
- Subjects with classical signs and symptoms of Tamaka Swasa.
- Subjects who are willing to give a written consent for the treatment.
- Subjects fit for Vamana.
- Subjects below 21 years and above 50 years of age.
- Subjects unfit for Vamana.
- Subjects who are having systemic disorders, which interfere with the treatment.
- Subjects who are on medication with Corticosteroids, anti-depressants and any other drug that may have an influence on the outcome of the study.
- Pregnant and lactating women.
- Severe attack of Tamaka Swasa having the peak flow expiratory rate.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method points that will be assessed as primary outcome : 0th day - Before commencement of treatment. | During treatment - Maximum days of treatment i.e.on 16th day i.e.day of Vamana. | Follow up - Maximum on 23rd day (7 days after Vamana) To analyse the effectiveness of Madhanaphala Dadhi yoga over Madhanaphala yoga in treating Tamaka Swasa/ Bronchial Asthma. Which can be further be used in clinical practice 0th day - Before commencement of treatment. | During treatment - Maximum days of treatment i.e.on 16th day i.e.day of Vamana. | Follow up - Maximum on 23rd day (7 days after Vamana) Morning worsening of asthma symptoms 0th day - Before commencement of treatment. | During treatment - Maximum days of treatment i.e.on 16th day i.e.day of Vamana. | Follow up - Maximum on 23rd day (7 days after Vamana) Swasa kshta (Shortness of breath) 0th day - Before commencement of treatment. | During treatment - Maximum days of treatment i.e.on 16th day i.e.day of Vamana. | Follow up - Maximum on 23rd day (7 days after Vamana) Shayana Swasapidita (breathlessness increase in lyin position) 0th day - Before commencement of treatment. | During treatment - Maximum days of treatment i.e.on 16th day i.e.day of Vamana. | Follow up - Maximum on 23rd day (7 days after Vamana) Use of bronchodilator 0th day - Before commencement of treatment. | During treatment - Maximum days of treatment i.e.on 16th day i.e.day of Vamana. | Follow up - Maximum on 23rd day (7 days after Vamana)
- Secondary Outcome Measures
Name Time Method Establishment of Madhanaphala Dadhi Yoga as one of the Aushadha Upakrama of Tamaka Swasa, which can further be used in Ayurvedic clinic practice points that will be assessed as secondary outcomes.
Trial Locations
- Locations (1)
SRI SRI COLLEGE OF AYURVEDIC SCIENCE AND RESEARCH
🇮🇳Bangalore, KARNATAKA, India
SRI SRI COLLEGE OF AYURVEDIC SCIENCE AND RESEARCH🇮🇳Bangalore, KARNATAKA, IndiaDr Niti Y LaheruPrincipal investigator7359012062drnitilaheru9@gmail.com