The Study of Post-operation Delirium and Prognosis of Cardiac Surgery Patients
- Conditions
- Delirium
- Interventions
- Device: quantitative electroencephalogram (qEEG)
- Registration Number
- NCT03351985
- Lead Sponsor
- Southeast University, China
- Brief Summary
Delirium is the most common neurological complication of cardiac surgery patients and associated with poor prognosis. In recent years, the important role of quantitative electroencephalogram (qEEG) in brain function monitoring is becoming increasingly prominent. The purpose of this study is to evaluate the effect of qEEG in predictive of post-operation delirium and prognosis of cardiac surgery patients.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 56
- The patients of cardiac surgery aged ≥18 years
- Signed informed consent
- Patients with a history of any neurologic and psychiatric disease
- Cognitive disorder
- Stroke history in three years
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Non-delirium Group quantitative electroencephalogram (qEEG) The cardiac surgery patients without delirium receive the quantitative electroencephalogram (qEEG) monitoring within 1 hour when they admitted to ICU Delirium Group quantitative electroencephalogram (qEEG) The cardiac surgery patients with delirium receive the quantitative electroencephalogram (qEEG) monitoring within 1 hour when they admitted to ICU
- Primary Outcome Measures
Name Time Method amplitude integrated electroencephalogram (aEEG) 24 hours the electroencephalogram amplitude of cardiac surgery patients assessed by quantitative electroencephalogram when admitted to intensive care unit
- Secondary Outcome Measures
Name Time Method alpha frequency band energy 24 hours the percentage of alpha frequency band of cardiac surgery patients assessed by quantitative electroencephalogram when admitted to intensive care unit
beta frequency band energy 24 hours the percentage of beta frequency band of cardiac surgery patients assessed by quantitative electroencephalogram when admitted to intensive care unit
theta frequency band energy 24 hours the percentage of theta frequency band of cardiac surgery patients assessed by quantitative electroencephalogram when admitted to intensive care unit
delta frequency band energy 24 hours the percentage of delta frequency band of cardiac surgery patients assessed by quantitative electroencephalogram when admitted to intensive care unit
alpha variability 24 hours the variability of alpha frequency band of cardiac surgery patients assessed by quantitative electroencephalogram when admitted to intensive care unit
arterial oxygen saturation (SaO2) 24 hours the level of arterial oxygen saturation (SaO2) of cardiac surgery patients when admitted to intensive care unit
central venous oxygen saturation (ScvO2) 24 hours the level of central venous oxygen saturation(ScvO2) of cardiac surgery patients when admitted to intensive care unit
neuron specific enolase (NSE) 24 hours the level of neuron specific enolase (NSE) of cardiac surgery patients when admitted to intensive care unit
interleukin-6 (IL-6) 24 hours the level of interleukin-6 (IL-6) of cardiac surgery patients when admitted to intensive care unit
troponin i (TNI) 24 hours the level of troponin i (TNI) of cardiac surgery patients when admitted to intensive care unit
high-sensitivity C-reactive protein (hs-CRP) 24 hours the level of high-sensitivity C-reactive protein (hs-CRP) of cardiac surgery patients when admitted to intensive care unit
N-terminal pro brain natriuretic peptide (NT-pro-BNP) 24 hours the level of N-terminal pro brain natriuretic peptide (NT-pro-BNP) of cardiac surgery patients when admitted to intensive care unit