Tissue Doppler Imaging (TDI) Versus Electrocardiography (ECG) Interventricular Pacing Delay Optimization in Cardiac Resynchronization Therapy (CRT)
- Conditions
- Heart FailureCardiac Resynchronization Therapy
- Registration Number
- NCT01179997
- Lead Sponsor
- Hospital Clinic of Barcelona
- Brief Summary
The aim of this study was to compare the response to cardiac resynchronization therapy when the interventricular pacing interval was optimized by Tissue Doppler Imaging (TDI) to response when it was optimized following QRS width criteria.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 156
- Patients submitted to de novo implant due to conventional cardiac resynchronization therapy indications.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method 6-month echocardiographic response Reduction of the end-systolic volume (measured in mililiters according to transthoracic echocardiography) of \>10% as compared to the baseline value.
- Secondary Outcome Measures
Name Time Method 6-month clinical response Combined end-point consisting in no death due to cardiovascular reasons, no heart transplantation and distance increase of \>10% (measured in meters) in the 6-minute walking test.
Trial Locations
- Locations (1)
Hospital Clinic Universitari
🇪🇸Barcelona, Catalonia, Spain
Hospital Clinic Universitari🇪🇸Barcelona, Catalonia, Spain