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Tissue Doppler Imaging (TDI) Versus Electrocardiography (ECG) Interventricular Pacing Delay Optimization in Cardiac Resynchronization Therapy (CRT)

Phase 3
Completed
Conditions
Heart Failure
Cardiac Resynchronization Therapy
Registration Number
NCT01179997
Lead Sponsor
Hospital Clinic of Barcelona
Brief Summary

The aim of this study was to compare the response to cardiac resynchronization therapy when the interventricular pacing interval was optimized by Tissue Doppler Imaging (TDI) to response when it was optimized following QRS width criteria.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
156
Inclusion Criteria
  • Patients submitted to de novo implant due to conventional cardiac resynchronization therapy indications.
Exclusion Criteria

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
6-month echocardiographic response

Reduction of the end-systolic volume (measured in mililiters according to transthoracic echocardiography) of \>10% as compared to the baseline value.

Secondary Outcome Measures
NameTimeMethod
6-month clinical response

Combined end-point consisting in no death due to cardiovascular reasons, no heart transplantation and distance increase of \>10% (measured in meters) in the 6-minute walking test.

Trial Locations

Locations (1)

Hospital Clinic Universitari

🇪🇸

Barcelona, Catalonia, Spain

Hospital Clinic Universitari
🇪🇸Barcelona, Catalonia, Spain

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