Tissue Doppler Imaging (TDI) Versus Electrocardiography (ECG) Interventricular Pacing Delay Optimization in Cardiac Resynchronization Therapy (CRT)
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 156
- 试验地点
- 1
- 主要终点
- 6-month echocardiographic response
研究概览
简要总结
The aim of this study was to compare the response to cardiac resynchronization therapy when the interventricular pacing interval was optimized by Tissue Doppler Imaging (TDI) to response when it was optimized following QRS width criteria.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients submitted to de novo implant due to conventional cardiac resynchronization therapy indications.
排除标准
- 未提供
研究组 & 干预措施
Tissue Doppler Imaging (TDI) optimization
Interventricular pacing delay optimized according to Tissue-Doppler echocardiography
干预措施: Interventricular pacing delay optimization by using Tissue Doppler-derived displacement curves (Device)
Electrocardiographic optimization
Interventricular pacing delay optimized according to QRS width observation in the 12-lead surface electrocardiogram
干预措施: Electrocardiographic optimization of the interventricular pacing delay according to QRS width (Device)
结局指标
主要结局
6-month echocardiographic response
Reduction of the end-systolic volume (measured in mililiters according to transthoracic echocardiography) of \>10% as compared to the baseline value.
次要结局
- 6-month clinical response
研究者
Josep Lluis Mont Girbau
MD PhD
Hospital Clinic of Barcelona