MedPath

A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC

Recruiting
Conditions
Alopecia Areata
Psoriasis
Chronic Spontaneous Urticaria
Atopic Dermatitis
Hidradenitis Suppurativa
Vitiligo
Registration Number
NCT03661866
Lead Sponsor
Target PharmaSolutions, Inc.
Brief Summary

TARGET-DERM is a longitudinal, observational study of adult and pediatric patients being managed for Atopic Dermatitis and other Immune-Mediated Inflammatory Skin Conditions (IMISC) in usual clinical practice. TARGET-DERM will create a research registry of patients with IMISC within academic and community real-world practices in order to assess the safety and effectiveness of current and future therapies.

Detailed Description

TARGET-DERM is a longitudinal, observational study of adult and pediatric patients being managed for Atopic Dermatitis and other Immune-Mediated Inflammatory Skin Conditions (IMISC) in usual clinical practice. TARGET-DERM will create a research registry of patients with IMISC within academic and community real-world practices in order to assess the safety and effectiveness of current and future therapies.

The duration of follow-up for participants enrolled in the EU is limited to 5-years. Those within in US and Canada may consent to indefinite follow-up.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
15000
Inclusion Criteria
    1. Adults and children (all ages) with Atopic Dermatitis or other Immune-mediated Inflammatory Skin Conditions been prescribed any dermatologic treatment.
    1. Participant has plans for future visits at the site for continued management of IMISC.
Exclusion Criteria
    1. Inability to provide written informed consent/assent.
    1. Subjects participating in any interventional study or trial for IMISC treatment trial at the time of enrollment. Patients may be enrolled in TARGET-DERM once participation in the trial is complete. Note: Participants may be enrolled in other registries or studies where IMISC treatment outcomes are observed and/or reported (such as center-based registries).

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Evaluate Adverse Events of IMISC and treatment in Clinical Practice25 Years

Enable characterization of IMISC disease activity and comorbid medical conditions over time.

Characterize IMISC Treatment Regimens in Clinical Practice25 Years

Enable characterization of IMISC disease activity and comorbid medical conditions over time.

Evaluate Patient Outcomes in Clinical Practice25 Years

Enable characterization of IMISC disease activity and comorbid medical conditions over time.

Secondary Outcome Measures
NameTimeMethod
Evaluate Patient Reported Outcome (PRO) measures25 Years

Inform clinical practice by identifying the occurrence and impact of comorbid medical conditions on treatment regimens, utilize patient reported outcomes, and evaluate patient support programs.

Evaluate outcomes related to Patient Support Programs (PSPs)25 Years

Inform clinical practice by identifying the occurrence and impact of comorbid medical conditions on treatment regimens, utilize patient reported outcomes, and evaluate patient support programs.

Evaluate the relationship between IMISC and comorbid medical conditions25 Years

Inform clinical practice by identifying the occurrence and impact of comorbid medical conditions on treatment regimens, utilize patient reported outcomes, and evaluate patient support programs.

Trial Locations

Locations (63)

Clear Dermatology & Aesthetics Center/Investigative MD

🇺🇸

Scottsdale, Arizona, United States

Johnson Dermatology

🇺🇸

Fort Smith, Arkansas, United States

University of Arkansas for Medical Sciences

🇺🇸

Little Rock, Arkansas, United States

Arkansas Dermatology

🇺🇸

Little Rock, Arkansas, United States

First OC Dermatology

🇺🇸

Fountain Valley, California, United States

Center for Dermatology Cosmetic and Laser Surgery

🇺🇸

Fremont, California, United States

University of California

🇺🇸

Irvine, California, United States

University of California - San Diego/Rady Children's Hospital

🇺🇸

San Diego, California, United States

George Washington University

🇺🇸

Washington, District of Columbia, United States

Feinstein Dermatology and Cosmetic Surgery

🇺🇸

Hollywood, Florida, United States

Academic Alliance in Dermatology

🇺🇸

Tampa, Florida, United States

Integrated Dermatology of West Palm Beach

🇺🇸

West Palm Beach, Florida, United States

Lurie Children's Hospital/Northwestern University

🇺🇸

Chicago, Illinois, United States

Dawes Fretzin Dermatology/ Dawes Fretzin Clinical Research Group

🇺🇸

Indianapolis, Indiana, United States

The University of Kansas Medical Center

🇺🇸

Kansas City, Kansas, United States

Family Allergy and Asthma Research Institute

🇺🇸

Louisville, Kentucky, United States

DermAssociates, LCC

🇺🇸

Rockville, Maryland, United States

Integrated Dermatology of Massachusetts

🇺🇸

Quincy, Massachusetts, United States

University of Massachusetts Medical School

🇺🇸

Worcester, Massachusetts, United States

University of Minnesota

🇺🇸

Minneapolis, Minnesota, United States

Mayo Clinic

🇺🇸

Rochester, Minnesota, United States

Carl Thornblade, MD, PLLC

🇺🇸

Missoula, Montana, United States

South Lincoln Dermatology Clinic

🇺🇸

Lincoln, Nebraska, United States

Advanced Dermatology of the Midlands

🇺🇸

Omaha, Nebraska, United States

Dartmouth-Hitchcock Medical Center

🇺🇸

Lebanon, New Hampshire, United States

Windsor Dermatology

🇺🇸

East Windsor, New Jersey, United States

Linda Susan Marcus

🇺🇸

Wyckoff, New Jersey, United States

Montefiore Medical Center

🇺🇸

Bronx, New York, United States

Centurion Dermatology

🇺🇸

Brooklyn, New York, United States

The University of Buffalo

🇺🇸

Buffalo, New York, United States

Empire Dermatology

🇺🇸

East Syracuse, New York, United States

Forest Hills Dermatology Group

🇺🇸

Forest Hills, New York, United States

Greenwich Village Dermatology

🇺🇸

New York, New York, United States

Ichan School of Medicine

🇺🇸

New York, New York, United States

Advanced Allergy & Asthma, PLLC

🇺🇸

Rockville Centre, New York, United States

Allergy Partners of Western North Carolina

🇺🇸

Asheville, North Carolina, United States

UNC Dermatology

🇺🇸

Chapel Hill, North Carolina, United States

Wake Forest University Health Sciences

🇺🇸

Winston-Salem, North Carolina, United States

Ohio State University

🇺🇸

Columbus, Ohio, United States

Allergy, Asthma & Clinical Research Center

🇺🇸

Oklahoma City, Oklahoma, United States

Oregon Health and Science University

🇺🇸

Portland, Oregon, United States

Allergy and Clinical Immunology

🇺🇸

Pittsburgh, Pennsylvania, United States

The Medical University of South Carolina

🇺🇸

Charleston, South Carolina, United States

El Paso Dermatology Center

🇺🇸

El Paso, Texas, United States

North Texas Center for Clinical Research

🇺🇸

Frisco, Texas, United States

Asthma and Allergy Center

🇺🇸

Lewisville, Texas, United States

Center for Clinical Studies

🇺🇸

Webster, Texas, United States

Allergy Associates of Utah

🇺🇸

Murray, Utah, United States

University of Utah MidValley Dermatology

🇺🇸

Murray, Utah, United States

Virginia Commonwealth University

🇺🇸

Richmond, Virginia, United States

North Sound Dermatology

🇺🇸

Mill Creek, Washington, United States

Spokane Dermatology Clinic

🇺🇸

Spokane, Washington, United States

Dermatology Center for Skin Health

🇺🇸

Morgantown, West Virginia, United States

Children's Hospital of Wisconsin

🇺🇸

Milwaukee, Wisconsin, United States

Skin Centre for Dermatology

🇨🇦

Peterborough, Ontario, Canada

York Dermatology Clinic and Research Centre

🇨🇦

Richmond Hill, Ontario, Canada

Innovaderm Research, Inc.

🇨🇦

Montréal, Quebec, Canada

Saskatoon Dermatology Centre

🇨🇦

Saskatoon, Saskatchewan, Canada

Dermatologische Gemeinschaftspraxis Mahlow

🇩🇪

Mahlow, Bradenburg, Germany

Dr. Bernhard Korge

🇩🇪

Düren, NRW, Germany

UKSH- Institut für Entzündungsmedizin

🇩🇪

Lübeck, Schleswig-Holstein, Germany

Hospital Clinic de Barcelona

🇪🇸

Barcelona, Spain

Hospital Universitario La Princesa

🇪🇸

Madrid, Spain

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