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Vericel

🇺🇸United States
Ownership
-
Employees
314
Market Cap
$2.6B
Website
Introduction

Vericel Corp. engages in the research, product development, manufacture, and distribution of patient-specific, expanded cellular therapies for use in the treatment of patients with diseases. Its product portfolio includes MACI and Epicel. The MACI portfolio is FDA-approved product that applies the process of tissue engineering to grow cells on scaffolds using healthy cartilage tissue from the patient's own knee. The Epicel portfolio provide skin replacement for patients who have deep dermal or full thickness burns. The company was founded on March 24, 1989 and is headquartered in Cambridge, MA.

Clinical Trials

16

Active:2
Completed:10

Trial Phases

4 Phases

Phase 1:2
Phase 2:4
Phase 3:5
+1 more phases

Drug Approvals

1

FDA:1

Drug Approvals

CARTICEL

Approval Date
Feb 6, 2017
FDA

Clinical Trials

Distribution across different clinical trial phases (12 trials with phase data)• Click on a phase to view related trials

Phase 3
5 (41.7%)
Phase 2
4 (33.3%)
Phase 1
2 (16.7%)
Phase 4
1 (8.3%)

A Study of MACI in Patients Aged 17 to 65 Years With Symptomatic Chondral or Osteochondral Defects of the Ankle

Phase 3
Not yet recruiting
Conditions
Chondral Defect
Articular Cartilage Defect
Interventions
First Posted Date
2025-04-08
Last Posted Date
2025-04-08
Lead Sponsor
Vericel Corporation
Target Recruit Count
276
Registration Number
NCT06915233

A Study of MACI in Patients Aged 10 to 17 Years With Symptomatic Chondral or Osteochondral Defects of the Knee

Phase 3
Recruiting
Conditions
Chondral Defect
Articular Cartilage Defect
Osteochondritis Dissecans (OCD)
Articular Cartilage Disorder of Knee
Interventions
Procedure: microfracture
First Posted Date
2018-07-17
Last Posted Date
2024-12-02
Lead Sponsor
Vericel Corporation
Target Recruit Count
45
Registration Number
NCT03588975
Locations
🇺🇸

Stanford University, Palo Alto, California, United States

🇺🇸

Shriner's Hospital for Children Northern California, Sacramento, California, United States

🇺🇸

University of California Davis Health, Sacramento, California, United States

and more 9 locations

An Efficacy, Safety and Tolerability Study of Ixmyelocel-T Administered Via Transendocardial Catheter-based Injections to Subjects With Heart Failure Due to Ischemic Dilated Cardiomyopathy (IDCM)

Phase 2
Completed
Conditions
Ischemic Dilated Cardiomyopathy (IDCM)
First Posted Date
2012-08-23
Last Posted Date
2021-05-27
Lead Sponsor
Vericel Corporation
Target Recruit Count
114
Registration Number
NCT01670981
Locations
🇺🇸

Cardiology, P.C. & Center for Therapeutic Angiogenesis, Birmingham, Alabama, United States

🇺🇸

University of Alabama at Birmingham, Birmingham, Alabama, United States

🇺🇸

Mercy Gilbert Medical Center, Gilbert, Arizona, United States

and more 33 locations

An Efficacy and Safety Study of Ixmyelocel-T in Patients With Critical Limb Ischemia (CLI)

Phase 3
Completed
Conditions
Critical Limb Ischemia
First Posted Date
2011-12-02
Last Posted Date
2021-05-27
Lead Sponsor
Vericel Corporation
Target Recruit Count
41
Registration Number
NCT01483898
Locations
🇺🇸

Cardiology PC, Birmingham, Alabama, United States

🇺🇸

Cardio-Thoracic Surgeons, P.C., Birmingham, Alabama, United States

🇺🇸

University Of Alabama At Birmingham, Birmingham, Alabama, United States

and more 83 locations

Extension Study for Participants of MACI00206 Study of MACI® for the Treatment of Symptomatic Articular Cartilage Defects of the Knee

Completed
Conditions
Articular Cartilage Defects
First Posted Date
2010-12-02
Last Posted Date
2021-05-12
Lead Sponsor
Vericel Corporation
Target Recruit Count
128
Registration Number
NCT01251588
Locations
🇨🇿

Urazova nemocnice v Brne, Brno, Czechia

🇨🇿

University Hospital Na Bulovce- Department of Orthopaedic Surgery Postgraduate Medical Institute, Praha 8, Czechia

🇫🇷

Polyclinique Saint-Roch, Montpellier Cedex 2, France

and more 11 locations
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News

FDA Approves Arthroscopic Delivery for MACI Knee Cartilage Repair

The FDA has approved a supplemental Biologics License Application for arthroscopic delivery of MACI, an autologous cultured chondrocytes on a porcine collagen membrane, for knee cartilage repair.

FDA Approves NexoBrid for Pediatric Thermal Burn Treatment

The FDA has approved NexoBrid (anacaulase-bcdb) for eschar removal in pediatric patients with deep partial-thickness and full-thickness thermal burns.

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