1. ASPECT - ASIA PACIFIC EVALUATION OF CHEST PAIN TRIAL An observational study of the diagnostic utility of a biomarker panel in the assessment of patients presenting to asia-paciifc hospitals with chest pain of possible cardiac origi

Not Applicable

Completed

• Conditions: chest pain of possible cardiac origin; Cardiovascular - Coronary heart disease

• Registration Number: ACTRN12609000283279
• Lead Sponsor: Inverness Medical Innovations

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2009-05-15
• Study Completion: 2010-07-31
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 3582

Inclusion Criteria

Adults presenting to the trial hospital Emergency Department with chest pain of possible cardiac origin

Exclusion Criteria

Age < 18 years. Non-resident in country of recruitment. Patients for whom follow-up will not be possible either due to lack of onward contact address or because they will be overseas. Unable or unwilling to consent

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ASPECT:To prospectively validate an accelerated chest pain algorithm involving Troponin I, Creatine Kinase MB (CKMB) and Myoglobin Delta measurements over a 2 hour time period from presentation to the Emergency Department (ED) in patients with possible Acute Coronary Syndrome (ACS) using the Biosite Triage point of care multi-marker panel[At presention to ethe emergency departmetn at Christchurch Hospital and again 2 hours later]

Secondary Outcome Measures

Name	Time	Method
To determine the potential cost benefit of such a strategy in terms of case weight costing and bed days.[From presenation to the Emergency Department at trial hospital , then at 30 days and 1 year for all cause readmission(s) and/or death.]