Development of Human Laboratory Study Model of Cocaine Relapse Prevention II - 1

Phase 1

• Conditions: Cocaine-Related Disorders

• Registration Number: NCT00094315
• Lead Sponsor: National Institute on Drug Abuse (NIDA)

Brief Summary

To study of classical conditioning mechanisms associated with arousal, craving and cocaine use.

Detailed Description

This is a single-site, double-blind, placebo-controlled crossover study of classical conditioning mechanisms associated with arousal, craving and cocaine use.

Study Timeline

• Study Start: 2004-09
• Study First Submitted QC: 2004-10-14
• Study First Submitted: 2004-10-15
• Study First Posted: 2004-10-15
• Study Completion: 2005-07
• Status Verified: 2005-09
• Last Update Submitted: 2017-01-10
• Last Update Posted: 2017-01-11

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

• Be English-speaking volunteers who are cocaine dependent
• Be non-treatment seeking at the time of the study
• Meet DSM-IV criteria for cocaine dependence
• Have ECG showing normal sinus rhythm, normal conductivity, and non clinically significant arrhythmias
• Females must provide a negative pregnancy test and agree to use birth control
• Have baseline laboratory tests within normal limits

Exclusion Criteria

• Please contact site for more information

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Stimulated and non-stimulated craving
Cocaine assessment

Trial Locations

Locations (1)

University of Texas Health Science Center; 🇺🇸 San Antonio, Texas, United States