MicroRNA Expression and Function in Cutaneous Malignant Melanoma

Completed

• Conditions: Melanoma

• Registration Number: NCT00536029
• Lead Sponsor: Rigshospitalet, Denmark

Brief Summary

Spectrophotometric intracutaneous analysis (SIAscopy) is a new technique for imaging pigmented skin lesions and for diagnosing melanoma and non-melanoma skin cancer. The SIAscope is a portable system comprising of a laptop computer connected to a small handheld skin probe equipped with a light source. The skin lesion is interrogated with light of different wavelengths and the reflection spectra analysed by proprietary algorithms showing distribution, position and quantity of melanin, blood and collagen within the papillary dermis (the SIAgraphs). Earlier studies generated promising results and documented \>80% specificity and sensitivity of SIAscopy for melanoma diagnosis. It has been suggested that this technique could be used for the initial screening and selection of pigmented lesion for excision. In this work we addressed the usefulness of SIAscopy for the clinical diagnosis of pigmented malignant melanoma in a prospective, blinded design.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-02
• Study Completion: 2007-06
• Status Verified: 2007-09
• Study First Submitted: 2007-09-26
• Study First Submitted QC: 2007-09-26
• Last Update Submitted: 2007-09-26
• Study First Posted: 2007-09-27
• Last Update Posted: 2007-09-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 68

Inclusion Criteria

• Pigmented lesion

Exclusion Criteria

• No pigmented lesion

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Rigshospitalet; 🇩🇰 Copenhagen, Denmark