E-learning to Improve the Quality of Drug Prescribing in Hospitalized Elderly Patients

Not Applicable

Completed

• Conditions: Drug Use
• Interventions: Other: E-learning

• Registration Number: NCT02339792
• Lead Sponsor: Mario Negri Institute for Pharmacological Research

Brief Summary

This randomized controlled pragmatic study is aimed to set-up, assess and implement an integrated e-learning program of medical education in an hospital setting, focused on teaching and implementing CGA added to geriatric pharmacological notions (GPNs) to improve the quality of drug prescribing in elderly patients

Detailed Description

The integrated e-learning program (intervention group) is focused on teaching and implementing knowledge on CGA and GPNs to help clinicians to improve the quality of drug prescribing in the elderly.The GPNs is focused on pharmaco-epidemiological issues of drug prescribing, pharmacokinetic and pharmacodynamic changes during aging, topics in evaluating and managing polypharmacy, criteria to review the appropriateness of drug therapies and the clinical relevance of PDDI in the elderly. The control group receives only GPNs.

Study Timeline

• Study Start: 2012-11
• Primary Completion: 2013-09
• Study Completion: 2014-09
• Study First Submitted: 2014-12-16
• Status Verified: 2015-01
• Study First Submitted QC: 2015-01-12
• Last Update Submitted: 2015-01-12
• Study First Posted: 2015-01-15
• Last Update Posted: 2015-01-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 697

Inclusion Criteria

• people aged 75 years or older

Exclusion Criteria

• people aged 75 years or older
• refusal of consent to participate
• a life expectancy of less than 6 months

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control	E-learning	e-learning program of medical education, focused on teaching only geriatric pharmacological notions (GPNs)
Intervention	E-learning	e-learning program of medical education, focused on teaching and implementing Comprehensive Geriatric Assessment (CGA) added to geriatric pharmacological notions (GPNs)

Primary Outcome Measures

Name	Time	Method
Improvement of drug prescribing	Participants will be followed for the duration of hospital stay, an expected average of 12 days	The primary study objective is to evaluate whether an integrated e-learning program of medical education, focused on teaching and implementing CGA added to GPNs (intervention) is superior to delivering GPNs only (control) in reducing the prescription of potentially inappropriate medications (PID) or of potential drug-drug interactions (PDDI) during hospitalization and at hospital discharge in hospitalized elderly.; The primary outcome is the change in prescription of PID,as defined by Beers' criteria , or of PDDI related to the 20 drugs most frequently prescribed during hospital stay and at discharge.

Secondary Outcome Measures

Name	Time	Method
clinical outcomes (lenght of hospitalization, mortality, rehospitalization)	12 months	Secondary objectives are the assessment of: - the impact of the integrated e-learning intervention in terms of length of hospitalization, in-hospital and overall mortality, re-hospitalization and institutionalization during a follow-up of 12 months; - the persistence and the clinical impact on the enrolled patients of the effect of the integrated e-learning intervention on the improvement of quality of drug prescribing during a follow-up of 12 months.; Secondary outcomes are the persistence and the clinical impact of the integrated e-learning intervention on duration of hospitalization, rate of in-hospital and overall mortality, re-hospitalization and institutionalization during 12 months of follow-up.