The Efficacy of Color-Doppler Ultrasonography to Assess the Renal Blood Flow With the Estimation of GFR

• Conditions: Hypertension; Renal Failure

• Registration Number: NCT00470769
• Lead Sponsor: University of Roma La Sapienza

Brief Summary

It is generally assumed that renal blood flow is symmetric in the absence of renal artery stenosis. The importance of studying the function of both kidneys separately is because it cannot be assumed that they are functionally equal.The aim of the present study is to evaluate whether this is really in patients with essential hypertension and/or moderate kidneys loss.

Detailed Description

To validate color Doppler ultrasonography of renal arteries for the assessment of renal blood flow (RBF), we comparing left and right RBF estimates and their sum (total RBF) by echo-Doppler with data obtained by 99mTc-DTPA scintigraphy in 50 patients with hypertension and/or moderate renal failure, compared with 30 normal control subjects.

Study Timeline

• Study Start: 2006-09
• Status Verified: 2007-05
• Study Completion: 2007-05
• Study First Submitted: 2007-05-07
• Study First Submitted QC: 2007-05-07
• Last Update Submitted: 2007-05-07
• Study First Posted: 2007-05-08
• Last Update Posted: 2007-05-08

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 2006

Inclusion Criteria

• Patients with hypertension
• Patients with moderate renal insufficiency
• Normal subjects

Exclusion Criteria

• Patients with solitary kidney function
• Patients with renal artery stenosis
• Patients underwent renal angioplasty and stenting

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (3)

Giorgio Fuiano; 🇮🇹 Catanzaro, Italy

Rosario Cianci; 🇮🇹 Rome, Italy

University of Rome La Sapienza; 🇮🇹 Roma, Italy