Effect of Premedication with oral clonidine on hemodynamic status of patients

Phase 3

Recruiting

Conditions: The effect of oral clonidine on hemodynamic changes after thyroid surgery.
Other complications of anesthesia
T88.59

Registration Number: IRCT20140107016117N3

Lead Sponsor: Tabriz University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 100

Inclusion Criteria

All ASA II patients aged 18-60 years who are candidate for total elective thyroidectomy surgery.

Exclusion Criteria

Patients with systemic diseases(cardiovascular, pulmonary, liver and kidney,...)
Blood loss over 10%
Prediction of patients with difficult airways
Drug addiction
Use medicines Interfering with clonidine drugs such as Ibuprofen, Metalol, losartan, beta-blockers, diazepam and vitamin B12.

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Systolic and diastolic blood pressure. Timepoint: From the beginning of anesthesia to 30th minute,every 5 minutes and after that every 15minutes. Method of measurement: Mercury barometer.

Secondary Outcome Measures

Name	Time	Method
Mean arterial pressure(MAP). Timepoint: From the beginning of anesthesia to 30th minute,every 5 minutes and after that every 15minutes. Method of measurement: Mercury barometer.;Heart rate. Timepoint: From the beginning of anesthesia to 30th minute,every 5 minutes and after that every 15minutes. Method of measurement: Counting in each minutes.;Partial pressure of end tidal of carbondioxide. Timepoint: From the beginning of anesthesia and then every 30 minutes. Method of measurement: Using the Copnograph.;Saturation of peripheral oxygen. Timepoint: From the beginning of anesthesia and then every 30 minutes. Method of measurement: Via the Pulse Oximeter.