Skip to main content
Clinical Trials/NCT03486847
NCT03486847
Completed
Not Applicable

Postoperative Atelectasis in Pediatric Patients With Prone Position : Effect of Repetitive Alveolar Recruitment by Lung Ultrasound

Seoul National University Hospital1 site in 1 country74 target enrollmentMarch 29, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pulmonary Atelectasis, Postoperative
Sponsor
Seoul National University Hospital
Enrollment
74
Locations
1
Primary Endpoint
Incidence of pre-extubation atelectasis
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

This study evaluates the incidence of postoperative atelectasis after general anesthesia with prone position using lung ultrasound in children age < 3 years.

Detailed Description

Atelectasis is common in pediatric patients after general anesthesia. Particularly, infants are more likely to develop atelectasis or ventilation-perfusion imbalance after general anesthesia because of the immature ribs and respiratory muscles, the high compliance of the rib cage and a significant reduction in functional residual capacity (FRC) during general anesthesia. Previous studies have reported that alveolar recruitment and positive end-expiratory pressure (PEEP) can be used to reduce atelectasis in children. Also, previous studies have shown that the lung ultrasound can be used to evaluate the degree of atelectasis during general anesthesia in children. However, none of the previous studies investigated the incidence of atelectasis, the effect of alveolar recruitment, and the PEEP in pediatric patients under general anesthesia with prone position. The purpose of this study was to evaluate previously described parameters using lung ultrasound.

Registry
clinicaltrials.gov
Start Date
March 29, 2018
End Date
July 31, 2019
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Hee-Soo Kim

Professor

Seoul National University Hospital

Eligibility Criteria

Inclusion Criteria

  • Children undergoing general anesthesia with prone position
  • Endotracheal intubation and mechanical ventilation during general anesthesia
  • Operation time is more than 2 hours

Exclusion Criteria

  • Previous lung surgery
  • Any abnormal findings such as atelectasis, pneumothorax, pleural effusion, or pneumonia on preoperative chest X-ray
  • Researchers judge (to be inappropriate)

Outcomes

Primary Outcomes

Incidence of pre-extubation atelectasis

Time Frame: postoperative 10 minutes

Incidence of pre-extubation atelectasis accessed by lung ultrasound

Secondary Outcomes

  • Incidence of intraoperative hypotension(intraoperative)
  • Incidence of intraoperative and postoperative (within 12hr) desaturation(intraoperative and postoperative (within 12hr))
  • Incidence of intraoperative atelectasis after intubation(intraoperative)
  • Incidence of intraoperative atelectasis after position change to prone(intraoperative)

Study Sites (1)

Loading locations...

Similar Trials