Postoperative Atelectasis in Pediatric Patients With Prone Position : Effect of Repetitive Alveolar Recruitment by Lung Ultrasound
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 74
- 试验地点
- 2
- 主要终点
- Incidence of pre-extubation atelectasis
研究概览
简要总结
This study evaluates the incidence of postoperative atelectasis after general anesthesia with prone position using lung ultrasound in children age < 3 years.
详细描述
Atelectasis is common in pediatric patients after general anesthesia. Particularly, infants are more likely to develop atelectasis or ventilation-perfusion imbalance after general anesthesia because of the immature ribs and respiratory muscles, the high compliance of the rib cage and a significant reduction in functional residual capacity (FRC) during general anesthesia. Previous studies have reported that alveolar recruitment and positive end-expiratory pressure (PEEP) can be used to reduce atelectasis in children. Also, previous studies have shown that the lung ultrasound can be used to evaluate the degree of atelectasis during general anesthesia in children.
However, none of the previous studies investigated the incidence of atelectasis, the effect of alveolar recruitment, and the PEEP in pediatric patients under general anesthesia with prone position. The purpose of this study was to evaluate previously described parameters using lung ultrasound.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- — 至 3 Years(Child)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children undergoing general anesthesia with prone position
- •Endotracheal intubation and mechanical ventilation during general anesthesia
- •Operation time is more than 2 hours
排除标准
- •Previous lung surgery
- •Any abnormal findings such as atelectasis, pneumothorax, pleural effusion, or pneumonia on preoperative chest X-ray
- •Researchers judge (to be inappropriate)
结局指标
主要结局
Incidence of pre-extubation atelectasis
时间窗: postoperative 10 minutes
Incidence of pre-extubation atelectasis accessed by lung ultrasound
次要结局
- Incidence of intraoperative hypotension(intraoperative)
- Incidence of intraoperative and postoperative (within 12hr) desaturation(intraoperative and postoperative (within 12hr))
- Incidence of intraoperative atelectasis after intubation(intraoperative)
- Incidence of intraoperative atelectasis after position change to prone(intraoperative)
研究者
Hee-Soo Kim
Professor
Seoul National University Hospital
