Effect of Spironolactone in Acute kidney disease
Phase 3
- Conditions
- Health Condition 1: N178- Other acute kidney failure
- Registration Number
- CTRI/2020/01/023081
- Lead Sponsor
- Government of West Bengal
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients of Acute Kidney Disease, defined as patients with serum creatinine >1.5 times the baseline or egfr <60/ml/min/1.73m2 4weeks after onset of acute kidney injury.
Exclusion Criteria
Patients unable to provide informed or surrogate consent
Patients with serum potassium >4.5
Females who are pregnant ,lactating or unwilling to use contraception.
Patients who are hypotensive with BP < 90/60.
Patients with any absolute or relative contraindication for doing renal biopsy.
Patients with acute GN diagnosed clinically or by biopsy.
Patients with Clinically significant urinary tract obstruction , confirmed by imaging.
Patients with history of allergy to spironolactone.
Patients with history of any malignancy.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method