The effect of the low-dose spironolactone in post adolescent acne: a randomized, double-blind, placebo-controlled trial.
Phase 4
Completed
- Conditions
- acne vulgaris in women who age from 25ᇁ years oldspironolactonepostadolescent acne
- Registration Number
- TCTR20190417004
- Lead Sponsor
- Faculty of Medicine, Chulalongkorn University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 62
Inclusion Criteria
healty female with moderate degree acne age from 25-45 years old
no underlying hepatic or renal dysfuncions
no current topical or systemic medications which can aggrating or suppressing acne condition
Exclusion Criteria
patients who are preganacy or lactating.
patients who are suspected of polycystic ovarian diseases or other abnormalities predisposing to acne conditions.
patients with abnormal skin conditions on their face
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ration of participants who acheive acne severity score of 0 (clear) or almost clear(1) 3 months acne severity score,rate of adversed event reported 3 months number of events
- Secondary Outcome Measures
Name Time Method the change of total acne count from baseline 3 months the count of acne