combination therapy trial in COVID-19 patients
Not Applicable
- Conditions
- COVID19.COVID-19, virus identifiedU07.1
- Registration Number
- IRCT20201003048904N2
- Lead Sponsor
- Boushehr University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
admitted patients in Bushehr's Shohadaye_Khalije_Fars hospital due to COVID19 diagnosis confirmed by Rt-PCR
age equal or more than 20
Male and female OPD patients with confirmed or probable SARS-CoV-2 infection according to WHO and CDC definitions referred to Motahari Clinic.
Exclusion Criteria
pregnancy
positive history of spironolactone or DPP4 inhibitor consumption
contraindications for drug intervention consumption (Plasma Acid/base, Electrolyte or Glucose abnormalities)
hypersensitivity to drugs
patient dissatisfaction
intubation and mechanical ventilation at admission onset
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The blood oxygen saturation percentage is examined as an index of oxygenation status. Timepoint: first, third and fifth day of study. Method of measurement: pulsoxymeter.
- Secondary Outcome Measures
Name Time Method ung involvement description and percentage in lung HRCT scan. Timepoint: first and fifth day of study. Method of measurement: Lung HRCT scan which will be reported by a radiologist.