The application of platelet-rich fibrin (PRF) in the management of mandibular fracture

Phase 2

• Conditions: Postoperative bone healing of fracture mandible both sides using CT measurement.; Fracture mandible; Bone healing; Platelet-rich fibrin

• Registration Number: TCTR20240704007
• Lead Sponsor: Buriram Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-07-04
• Last Update Posted: 19 August 2024
• Study Completion: 2026-12-31

Recruitment & Eligibility

• Status: Enrolling by invitation
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1. Patient-age more than 18 years old who have bilateral mandibular fractures at symphisis, parasymphisis, body and angle areas of mandible
2. Malocclusion

Exclusion Criteria

1. Comminuted mandibular fractures
2. Age of fracture more than 21 days
3. Infection at fracture site
4. Severe underlying disease (severe cardiovascular disease, coagulopathy and hematologic disorder, uncontrol psychologic disorder)
5. HIV/ AIDS
6. Pregnancy
7. Patients who refuse to participate in the research project

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Fracture site healing at 2 weeks, 1 month and 3 months after surgery Hounsfield unit from CT facial bone

Secondary Outcome Measures

Name	Time	Method
none none none