Characterisation of regulatory T cells and cytokine production in children diagnosed with asthma
Completed
- Conditions
- Airway hyperresponsivenessbronchusobstruction100386861000170810006436
- Registration Number
- NL-OMON33976
- Lead Sponsor
- niversitair Medisch Centrum Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 120
Inclusion Criteria
Diagnosis asthma for more than one year
Use of inhaled corticosteroids for more than one year
Lung function reversibility of more than 10%
RAST test performed
OR
No asthma
Exclusion Criteria
The use of systemic immune modulating medication at the time of blood withdrawal and/or 6 weeks before blood withdrawal. Active infection at the time of blood withdrawal and/or the use of antibiotics at the time of blood withdrawal.
OR
Allergies and autoimmune diseases.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Number, phenotype and functionality of regulatory T cells in the peripheral<br /><br>blood.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Cytokine analysis in the peripheral blood</p><br>