Influence of macrolide maintenance therapy and bacterial colonisation on exacerbation frequency and progression of COPD, a randomized double-blind placebo-controlled trial
Phase 3
Completed
- Conditions
- chronic bronchitisemphysema10006436
- Registration Number
- NL-OMON36440
- Lead Sponsor
- Amphia Ziekenhuis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 92
Inclusion Criteria
COPD patients who have had 3 or more exacerbations in the previous year, which have been treated with antibiotics and/or corticosteroids.
Exclusion Criteria
Use of antibiotics or a course of high doses of systemic steroids defined as more than 10 mg of prednisone a day within a month prior to involvement in the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Reduction in the number of exacerbations in the year of treatment.</p><br>
- Secondary Outcome Measures
Name Time Method