Pilot Study: Iron-chelating treatment in patients with Neurodegeneration with Brain Iron Accumulation (NBIA). - ND

• Conditions: patients with NBIA; MedDRA version: 9.1Level: SOCClassification code 10029205Term: Nervous system disorders

• Registration Number: EUCTR2008-005206-39-IT
• Lead Sponsor: AZIENDA OSPEDALIERA OSPEDALI GALLIERA

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2008-11-26
• Last Update Posted: 19 March 2012

Recruitment & Eligibility

• Status: Authorised-recruitment may be ongoing or finished
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Patients aged ≥ 18 years affected from a neurological de generation with brain iron accumulation documented by RMI and who do not present sistemyc iron overload escluded by RMI and/or SQUID, MID, Needle Liver Biopsy. Patients who signed and witnessed written informed consent.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Patients unable to undergo MRI. Patients with serum creatinine > 1.5 mg/dl. History of malignancy of any organ system. Patients with cardiovascolar, renal and liver deseases that do not allow the administration of the study drug. Hypersensitivity to deferiprone
Patients unwilling or unable to comply with the protocol. Pregnant or breastfeeding women are not elegible to partecipate in the study

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified