MedPath

Substance Use and Lifestyle-related Health Problems in Ageing Patients in OMT Treatment

Completed
Conditions
Health, Subjective
Substance Use Disorders
Opioid Use Disorder
Tobacco Use
Mental Health Impairment
Interventions
Other: Substance use disorder treatment
Registration Number
NCT05182918
Lead Sponsor
Sorlandet Hospital HF
Brief Summary

The overall aim of the study is to explore substance use, tobacco use and lifestyle-related health problems among ageing patients in Opioid Maintenance Treatment (OMT), and other SUD treatment.

The study will use already collected data from the multi-center, longitudinal, observational NorComt study (Norwegian Cohort of Patients in Opioid Maintenance Treatment and Other Drug Treatment study).

NorComt is the largest longitudinal study of SUD patients in Norway. The data consists of data from OMT and other substance use disorders (SUD) treatment (N=548).

Detailed Description

The overall aim of the study is to explore substance use, tobacco use and lifestyle-related health problems among ageing patients in Opioid Maintenance Treatment (OMT), and other SUD treatment.

The study will use already collected data from the multi-center, longitudinal, observational NorComt (Norwegian Cohort of Patients in Opioid Maintenance Treatment and Other Drug Treatment) study.

NorComt is the largest longitudinal study of SUD patients in Norway. The data consists of data from OMT and other substance use disorders (SUD) treatment (N=548).

The present doctoral research degree project is financed by the Southern and Eastern Norway Regional Health Authority, and hosted by Sørlandet hospital in collaboration with the Norwegian Centre for Addiction Research (SERAF).

Ethical approval for analysis of NorComt data and for the planned registry data linkages of NorComt data has been granted by the Norwegian Regional Ethics Committee (REK 2012/1131).

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
548
Inclusion Criteria
  • Admittance to a substance use disorder treatment facility, either standardized opioid maintenance treatment (OMT) or other substance use disorder treatment (in-patient)
Exclusion Criteria
  • None

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Patients in OMT and other SUD treatmentSubstance use disorder treatmentPatients in opioid maintenance treatment and other substance use disorder treatment
Primary Outcome Measures
NameTimeMethod
Substance useApproximately one year after admission to treatment (range 11 - 18 months)

Changes in substance use from baseline to follow-up. Excerpts from the European version were used to collect data on substance use. Substance use was scored for the previous 4 weeks on a 6-point response format were 0 corresponded to "No use" and 5 corresponded to "Daily use". 1 year follow-up were compared with baseline values.

Somatic complaints.Approximately one year after admission to treatment (range 11 - 18 months).

Changes in somatic complaints from baseline to follow-up. A checklist containing 16 somatic complaints common among chronic drug users, including major organ systems. Responses are provided on a 0 -4 response format, with 0 corresponding to "not at all", 1 "a little", 2 "moderately", 3 "a lot", and 4 "very much".

Tobacco useApproximately one year after admission to treatment (range 11 - 18 months)

Changes in tobacco use from baseline to follow-up

Secondary Outcome Measures
NameTimeMethod
Mental distressApproximately one year after admission to treatment (range 11 - 18 months)

Changes from baseline to post-treatment and follow-up. The Hopkins Symptom Checklist (HSCL) 25-item version was used to measure mental distress. Each of the 25 items was scored on a 5-point scale (0-4). An average score was computed, indicating a global severity index of mental distress (GSI).

QoL (quality of life)Approximately one year after admission to treatment (range 11 - 18 months)

Excerpts from the QoL10 will be used to assess QoL. The scale has 10 ordinal items and each item is scored from 1 = very poor up to 5 = very good. The scale is transformed to a decimal scale ranging from 0.1 to 0.9 and averaged, where 0.9 is the best QoL. A normative score in a population sample was 0.7.

Trial Locations

Locations (1)

Addiction Unit - Sørlandet Hospital

🇳🇴

Kristiansand, Agder, Norway

© Copyright 2025. All Rights Reserved by MedPath