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Clinical Trials/NCT03405311
NCT03405311
Terminated
Not Applicable

3D Ultrasound-guided Labor Epidural Analgesia in the Morbid Obese Parturient: A Randomized Control Trial

The University of Texas Medical Branch, Galveston1 site in 1 country40 target enrollmentFebruary 20, 2018

Overview

Phase
Not Applicable
Intervention
Palpation
Conditions
Obesity, Morbid
Sponsor
The University of Texas Medical Branch, Galveston
Enrollment
40
Locations
1
Primary Endpoint
Number of Needle Insertion Attempts Calculated Across All Participants
Status
Terminated
Last Updated
2 months ago

Overview

Brief Summary

This study will be a randomized control study, with the objective to evaluate epidural analgesia success rates between the two methods (Blind Approach versus Accuro Device).

Detailed Description

Worldwide obesity has become an epidemic. The obstetrical population is no exception. This made more challenging for anesthesiologists on labor and delivery units to administer epidural analgesia. According to the World Health Organization, more than 30% of U.S. adults are obese with a body mass index (BMI; in kg/m2) ≥ 30. Recent data has shown that increased BMI has been associated with increased neuraxial analgesic failure and difficulty with prolonged epidural placement time. The 'Blind approach' is the current standard of care in administering neuraxial anesthesia. The physician palpates the patient's spinal bony landmarks; the needle is placed in relation to identified landmarks and inserted until loss of resistance is felt. In the obese population, the success rates are as low as 68%. Recently the FDA has approved a handheld device "The Accuro" as an adjunct for neuraxial analgesia (Rivanna Medical, LLC). It consists of a three-dimensional ultrasound device. By utilizing sound waves it constructs three-dimensional images of the spinal column, allowing the physician to better see the spine in order to perform spinal/epidural anesthesia. Hypothesize that this device will enable clinicians to assess epidural spaces for epidural needle placement compared with the traditional Blind approach in the morbidly obese parturient. This study will be a randomized control study, with the objective to evaluate epidural analgesia success rates between the two methods (Blind Approach versus Accuro Device). Also, will determine if ultrasound based landmarks would reduce the needle tract and thereby reduced the amount of post-procedure pain at the insertion site in the peripartum period by using the algometer.

Registry
clinicaltrials.gov
Start Date
February 20, 2018
End Date
January 11, 2024
Last Updated
2 months ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Eligibility Criteria

Inclusion Criteria

  • American Society of Anesthesiologists physical status class I, II, or III.
  • Term pregnancy.
  • Requesting epidural analgesia for anticipated vaginal delivery.
  • BMI\>or = 40.

Exclusion Criteria

  • Contraindication for epidural analgesia
  • Inability to adequately understand the consent form.
  • Incarcerated patients.
  • Patients with known spinal deformities.
  • Allergies to ultrasound gel.
  • Allergies to local anesthetics

Arms & Interventions

Palpation

The control group (Group 2: Epidural) will receive the 'Blind/standard approach', which is the current standard of care using palpation in administering labor epidural analgesia. Additionally, an anesthesiologist will scan patient's back with Accuro device in turn off mode.

Intervention: Palpation

Rivanna Accuro 3D Ultrasound Device

The treatment group (Group 1: Ultrasound and Epidural) will receive epidural analgesia using ultrasound pre-procedural scan with the ACCURO device.

Intervention: Rivanna Accuro 3D Ultrasound Device

Outcomes

Primary Outcomes

Number of Needle Insertion Attempts Calculated Across All Participants

Time Frame: Beginning of needle insertion till catheter placement-15 minutes

An epidural insertion attempt will be defined as advancement of the needle in an effort to enter the epidural space; a needle requiring withdrawal for redirection or reinsertion through the skin/another skin puncture will be counted as an additional attempt.

Number of Participants With Successful Epidural Catheter Placements

Time Frame: Within first 90 minutes following catheter placement

Number of Participants With Successful Epidural Catheter Placements.

Number of Needle Insertion Redirections Calculated Across All Participants

Time Frame: Beginning of needle insertion till catheter placement-15 minutes

An epidural insertion attempt will be defined as advancement of the needle in an effort to enter the epidural space; a needle requiring withdrawal for redirection or reinsertion through the skin/another skin puncture will be counted as an additional attempt.

Secondary Outcomes

  • Procedural Difficulty Rated by the Performing Anesthesiologist on a 10-point Likert Scale(Beginning of needle insertion till catheter placement-15 minutes)
  • Needle Depth(Beginning of needle insertion till catheter placement-15 minutes)
  • Pressure Pain Thresholds(Before epidural placement)
  • Number of Complications Recorded Calculated Across All Participants(Within 30 days of admission)

Study Sites (1)

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