The Relationship of DASH and Mediterranean Diet Score With Serum Adiponectin Levels in Patients With Spinal Cord Injury

Completed

• Conditions: Spinal Cord Injuries
• Interventions: Other: Keeping a 1-day food consumption record by the patient; Other: Measurement of adiponectin level

• Registration Number: NCT05997251
• Lead Sponsor: Ankara City Hospital Bilkent

Brief Summary

The aim of this study is to reveal the relationship of DASH and Mediterranean diet score with anthropometric measurements and serum adiponectin level in individuals with spinal cord injury. This research was planned as a cross-sectional, case-control study. With the data to be obtained from the research, information will be obtained about the hormonal or biochemical basis of metabolic disorders such as atherosclerosis and insulin resistance that may occur in individuals with spinal cord injury in the long term.

20 individuals with Spinal Cord Injury will be included in the study, and the results of the patients will be compared with 20 healthy individuals. In order to determine the food consumption status of the patients, a 1-day food consumption record will be requested. DASH diet score and Mediterranean diet score will be calculated from dietary records. After 8 hours of fasting, 3 ml of peripheral blood will be taken for the measurement of adiponectin between 08:00 and 09:00 in the morning from the individuals in the study and control groups. Adiponectin level will be measured and its correlation with DASH diet score and Mediterranean diet score will be examined.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-03-01
• Primary Completion: 2022-03-01
• Study Completion: 2022-03-01
• Status Verified: 2023-08
• Study First Submitted: 2023-08-10
• Study First Submitted QC: 2023-08-10
• Last Update Submitted: 2023-08-10
• Study First Posted: 2023-08-18
• Last Update Posted: 2023-08-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 66

Inclusion Criteria

• Inclusion criteria (Study group)

  • Having spent at least 6 months after spinal cord injury
  • 1st motor neuron injury
  • Being between the ages of 18-65
  • Giving consent to participate in the study Inclusion criteria (Control group)
  • Being between the ages of 18-65
  • Giving consent to participate in the study

Exclusion Criteria

• Exclusion criteria (Study group)

  • Having an additional disease to the spinal cord injury
  • Having a 2nd motor neuron lesion

Exclusion criteria (Control group)

• Having any disease

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients with spinal cord injury	Keeping a 1-day food consumption record by the patient	-
Healthy group	Measurement of adiponectin level	-
Patients with spinal cord injury	Measurement of adiponectin level	-
Healthy group	Keeping a 1-day food consumption record by the patient	-

Primary Outcome Measures

Name	Time	Method
Adiponectin level	Will be measured at inclusion	Adiponectin level will be measured from peripheral blood
Mediterrenian diet score	Will be measured at inclusion from one day dietary record	Will be measured at inclusion from one day dietary record
DASH diet score	Will be measured at inclusion from one day dietary record	Will be measured at inclusion from one day dietary record

Secondary Outcome Measures

Name	Time	Method
Fasting blood glucose	Will be measured at inclusion	Will be measured at inclusion
HDL	Will be measured at inclusion	Will be measured at inclusion
TG	Will be measured at inclusion	Will be measured at inclusion
Whole blood count	Will be measured at inclusion	Will be measured at inclusion
Total cholesterol	Will be measured at inclusion	Will be measured at inclusion
LDL	Will be measured at inclusion	Will be measured at inclusion

Trial Locations

Locations (1)

Ankara Bilkent City Hospital Physical Treatment and Rehabilitation Hospital; 🇹🇷 Ankara, Turkey