A Comparison of Fluconazole and Amphotericin B in the Treatment of Cryptococcal Meningitis
- Conditions
- Meningitis, CryptococcalHIV Infections
- Registration Number
- NCT00002305
- Lead Sponsor
- Pfizer
- Brief Summary
To compare the safety and effectiveness of fluconazole and amphotericin B, alone or in combination with flucytosine, as treatment for acute cryptococcal meningitis.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- Not specified
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (45)
UCLA CARE Ctr
🇺🇸Los Angeles, California, United States
Emory Univ School of Medicine
🇺🇸Atlanta, Georgia, United States
DeKalb Gen Hosp
🇺🇸Decatur, Georgia, United States
Dr Michael Bach
🇺🇸Portland, Maine, United States
Univ of Maryland / Inst of Human Virology
🇺🇸Baltimore, Maryland, United States
Albany Med College / AIDS Treatment Ctr
🇺🇸Albany, New York, United States
Dr Daniel Barbaro
🇺🇸Dallas, Texas, United States
Dr Shelly Gordon
🇺🇸San Francisco, California, United States
Univ Hosp
🇺🇸Boston, Massachusetts, United States
Henry Ford Hosp
🇺🇸Detroit, Michigan, United States
Dr Martin Mass
🇺🇸San Francisco, California, United States
Harper Hosp
🇺🇸Detroit, Michigan, United States
Cincinnati Veterans Adm Med Ctr / Univ Hosp
🇺🇸Cincinnati, Ohio, United States
CHG-118 Group Health / Cooperative of Puget Sound
🇺🇸Seattle, Washington, United States
New England Med Ctr
🇺🇸Boston, Massachusetts, United States
Northwestern Univ Med School
🇺🇸Chicago, Illinois, United States
Tulane Univ School of Medicine
🇺🇸New Orleans, Louisiana, United States
Christiana Hosp / Med Ctr of Delaware
🇺🇸Wilmington, Delaware, United States
Univ of Miami School of Medicine
🇺🇸Miami, Florida, United States
Dr Paul Rothman
🇺🇸Sherman Oaks, California, United States
Univ of Alabama at Birmingham
🇺🇸Birmingham, Alabama, United States
Tucson Veterans Administration Med Ctr
🇺🇸Tucson, Arizona, United States
Washington Univ School of Medicine
🇺🇸St. Louis, Missouri, United States
Med College of Georgia
🇺🇸Augusta, Georgia, United States
Montefiore Med Ctr / Bronx Municipal Hosp
🇺🇸Bronx, New York, United States
Bronx Veterans Administration / Mount Sinai Hosp
🇺🇸Bronx, New York, United States
Jewish Hosp Ctr Affiliation
🇺🇸Jamaica, New York, United States
Ohio State Univ Hosp
🇺🇸Columbus, Ohio, United States
Univ TX Galveston Med Branch
🇺🇸Galveston, Texas, United States
United States Air Force Med Ctr
🇺🇸Lackland Air Force Base, Texas, United States
Saint Michael's Hosp
🇨🇦Toronto, Ontario, Canada
Univ TX San Antonio Health Science Ctr
🇺🇸San Antonio, Texas, United States
Univ of South Florida
🇺🇸Tampa, Florida, United States
Ann Arbor Veterans Administration Med Ctr
🇺🇸Ann Arbor, Michigan, United States
George Washington Univ Med Ctr
🇺🇸Washington, District of Columbia, United States
Louisiana State Univ School of Medicine
🇺🇸New Orleans, Louisiana, United States
Loch Raven Veterans Hosp
🇺🇸Baltimore, Maryland, United States
Saint Luke's - Roosevelt Hosp Ctr
🇺🇸New York, New York, United States
Mem Sloan - Kettering Cancer Ctr
🇺🇸New York, New York, United States
Chelsea Village Med Ctr
🇺🇸New York, New York, United States
Univ of North Carolina School of Medicine
🇺🇸Chapel Hill, North Carolina, United States
Columbia Univ
🇺🇸New York, New York, United States
Univ of Tennessee
🇺🇸Memphis, Tennessee, United States
Harlem AIDS Treatment Group / Harlem Hosp Ctr
🇺🇸New York, New York, United States
Richmond AIDS Consortium
🇺🇸Richmond, Virginia, United States