Comparison of the effects of Citalopram Versus Fluoxetine on motor function after stroke.
- Conditions
- Cerebral infarction.Sequelae of cerebral infarction
- Registration Number
- IRCT20141116019971N3
- Lead Sponsor
- Vice chancellor for research, Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 90
Over 18 years of age
Suffering from hemiparesis or hemiplegia as a result of a first-time acute (in the past 24 hours) ischemic stroke
An initial Fugl-Meyer Motor Scale score of under 55
A National Institutes of Health Stroke Scale score of less than five
Prior disabilities including aphasia, cognitive disorders and motor disorders due to stroke or any other neurodegenerative disease
Pregnancy or breastfeeding
Currently taking antidepressants
Contraindications of therapy, including renal insufficiency (glomerular filtration rate <30 ml/min), abnormal liver function tests, hyponatremia and a long QT interval on an electrocardiogram and
Any significant adverse effects (agitation, hypertension or other signs of serotonin syndrome) after initiation of treatment
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Motor function. Timepoint: At recruitment and after 90 days. Method of measurement: Fugl-Meyer Motor Scale score.
- Secondary Outcome Measures
Name Time Method