Variation IGFBP7 Markers and TIMP2 Induced by Injection of Contrast Iodized Drug at the Intensive Care Patient
Completed
- Conditions
- Emergency
- Registration Number
- NCT02881710
- Lead Sponsor
- Nantes University Hospital
- Brief Summary
Multicenter, prospective, uncontrolled study to evaluate variations in urinary concentrations of TIMP-2 and PCI IGFBP7 induced injection during a CT scan in intensive care patient.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
- Patients aged 18 years or more,
- Hospitalized in intensive care,
- Holders of a urinary catheter
- Patient receiving a first CT with intravenous injection of PCI during their ICU stay.
- Patient agreeing to participate in the research protocol
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Exclusion Criteria
- Anuria
- Need to retain urine, whatever the reason (eg measurement of 24-hour proteinuria).
- Urine unanalyzable whatever reason (eg urinary washing with double current probe, injection is saline to measure bladder pressure.).
- Patient subjected to renal replacement
- Patient already included in the study for a previous injection of PCI in intensive care.
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Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method significant increase in urinary concentrations of TIMP-2 and IGFBP7 defined as an increase of NephroCheck® test of more than 0.2 [ng / mL] 2/1000) after PCI injection follow up: 5 days after injection
- Secondary Outcome Measures
Name Time Method