Perioperative management of direct oral anticoagulants in urological surgery
Not Applicable
Recruiting
- Conditions
- All urological patients on DOACs undergoing elective surgical intervention
- Registration Number
- DRKS00033173
- Lead Sponsor
- niversitätskllinik Mannheim, Abteilung für Urologie und Urochirurgie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 476
Inclusion Criteria
Patient age = 18 years (with atrial fibrillation, history of deep vein thrombosis, and left atrial enlargement).
- Long-term therapy with a direct oral anticoagulant (Rivaroxaban, Apixaban, Dabigatran, or Edoxaban).
- Elective urological operation.
Exclusion Criteria
- Mechanical heart valve and/or use of vitamin K antagonists.
- Patients with GFR (glomerular filtration rate) < 30 ml/min (Dabigatran).
- Patients with GFR < 15 ml/min (Apixaban, Rivaroxaban).
- Ongoing dual antiplatelet therapy (ADP receptor blocker, P2Y12).
- Patients planned for cystectomy with urinary diversion.
- Cognitive limitations or psychiatric conditions preventing adherence to the study protocol.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Major Bleeding Events
- Secondary Outcome Measures
Name Time Method Secondary Endpoints:<br> - minor bleeding bleeding events<br>- mortality<br>- thromboembolic Events<br>- Non-adherence to study protocoll