A randomized control trial of the effect of restricted protein diet to delay renal replacement therapy in septic patients with acute renal failure

Phase 1

Completed

• Conditions: - acute kidney injury stage 2 or above (from KDIGO staging)- septic shock patient

• Registration Number: TCTR20180217001
• Lead Sponsor: Sanit Wichansawakun

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-02-17
• Study Completion: 2018-11-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 74

Inclusion Criteria

- acute kidney injury stage 2 within 48 hour
- septic shock require inotrophic drug
- on tube feeding or parenteral nutrition
- no nutritional support contraindication

Exclusion Criteria

- reject current disease management
- on renal replacement therapy in past or within 24 hour after acute kidney injury diagnosis
- acute kidney injury from renal artery, glomerulonephritis, interstitial nephritis, vasculitis, post renal obstruction, hemolytic uremic syndrome, thrombotic thrombocytopenia purpura, hepatorenal syndrome, cardiorenal syndrome
- Very high catabolism (burn)
- protein-losing enteropathy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
timing from AKI to dialysis timing from AKI to dialysis logrank test

Secondary Outcome Measures

Name	Time	Method
30 day mortality rate 30 days persent,infection complication rate 30 days persent