Electrolytes and small organic molecules in blood and sweat during an incremental cycling protocol

Completed

• Conditions: Geen aandoeningen; Er wordt geen aandoening bestudeerd

• Registration Number: NL-OMON48178
• Lead Sponsor: Vrije Universiteit

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 24 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 12

Inclusion Criteria

- 18-40 years old
- Generally healthy: no cardiac problems (according to NYHA classification), no
high blood pressure, no fever or infection, no psychiatric problems, no liver
and kidney problems
- Command of the Dutch language
- Fit (actively taking part in sports 3 times a week)
- Body mass index (BMI) 20-25 kg/m2
- Veins suitable for blood sampling at the inspection
- Based on the outcome of the anamnesis form, participants should be rated as
low-risk participants

Exclusion Criteria

A potential subject who meets any of the following criteria will be excluded
from participation in this study:
- Underage
- Older than 40 years
- Smoking
- Use of hard drugs
- Use of specific medicines:
* Chronic use of NSAIDs: aspirin, ibuprofen, corticosteroids
* Drugs for gastric and intestinal function
* Drugs for heart and coronary diseases
- Blood donation six weeks prior to the start of the study
- Pregnancy or breastfeeding
- Sweat pattern condition: hyperhidrosis, hypohidrosis or anhidrosis
- No low-risk classification based on the outcome of the anamnesis form (see
appendix xxx)

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>[Na+], [K+], [Cl-], [NH3+], [lactate] in blood and sweat.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Level of fitness, age, sex, core temperature, heart rate, skin temperature,<br /><br>subjective measures, whole body sweat rate, urine specific gravity (USG), food<br /><br>intake. </p><br>