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临床试验/NCT05511857
NCT05511857招募中不适用

Self-distancing and Pain: Can Different Thinking Strategies Affect the Perception of Short-lasting and Long-lasting, Persistent Pain?

Linnaeus University1 个研究点 分布在 1 个国家目标入组 292 人开始时间: 2022年9月7日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
292
试验地点
1
主要终点
Pain tolerance

研究概览

简要总结

Physical pain leads to a narrow, egocentric focus on the self, in the here and now, particularly when experienced at high intensity levels. When long-term pains are experienced, this narrow focus could be debilitating, since attention to the pain itself may increase its perceived intensity and it could increase negative emotional processes that further contribute to pain-related suffering. One way of overcoming this could be by adopting a more distant view of oneself and the pain, thereby making the pain more abstract. An established way of creating distance is by reflecting on the self, using one's own name and second or third-person singular pronouns, so called third-person self-talk. Earlier research has reported that a psychologically distant perspective could reduce emotional distress when reflecting on negative experiences, reduce feelings of anger after provocation and to lower blood pressure. Self-distancing should thus help people mentally reconstrue their pain experience and possibly make the pain signals less cognitively salient. In this experimental study, healthy participants will be induced with pain while performing different tasks.

详细描述

Physical pain leads to a narrow, egocentric focus on the self, in the here and now, particularly when experienced at high intensity levels. When long-term pain is experienced, this narrow focus could be debilitating, since attention to the pain itself may increase its perceived intensity and it could increase negative emotional processes that further contribute to pain-related suffering. One way of overcoming this could be by adopting a more distant view of oneself and the pain, thereby making the pain more abstract. An established way of creating distance is by reflecting on the self, using one's own name and second or third-person singular pronouns, so called third-person self-talk. Earlier research has reported that a psychologically distant perspective could reduce emotional distress when reflecting on negative experiences, reduce feelings of anger after provocation and lead to lower blood pressure. Self-distancing should thus help people mentally reconstrue their pain experience and possibly make the pain signals less cognitively salient.

In the first part of this study, which will be the first registered on ClinicalTrials.gov, we will experimentally induce pain in healthy participants (N = 292) with a cold pressor apparatus. The cold pressor apparatus holds a constant water temperature of 1 degree Celsius, which creates pain in the immersed hand. At the experimental test session, the participant will first be comfortably seated and receive information about the task and the experimental pain induction. They will be instructed to withhold their hand in the cold water for as long as possible, but when they feel that the pain becomes too intense they can choose to remove their hand. After that, a blood pressure measurement will be conducted. Directly after that, the participant will be instructed to put their hand in the cold water-bath (the cold pressor apparatus), and when they put their hand in the cold water a new blood pressure measurement will be conducted. A timer will be started to measure the time in seconds that the participant is able to keep their hand in the cold water. While their hand is in the cold water-bath, the participant will conduct one of the four different interventions (self-distanced, third-person self-talk following a cue-card; self-immersed, first-person self-talk following a cue-card; distraction intervention following a cue-card; no intervention (control)). When the participant removes their hand from the cold water-bath, the time in seconds will be noted and they will immediately be asked to estimate their pain on a Numerical Rating Scale. A short debriefing will conclude the session.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • •No known disease affecting the nervous system.
  • •Swedish comprehension.
  • •Age over 18 years old.

排除标准

  • •Experiencing clinical pain at the test session.
  • •Known disease affecting the nervous system.
  • •Inadequate Swedish comprehension.
  • •Age under 18 years old.

研究组 & 干预措施

The effect of a self-distanced view on pain perception.

Experimental

The participant will exert self-distanced, third-person self-talk following a cue-card while induced with experimental pain.

干预措施: Self-distancing, third-person self-talk. (Behavioral)

The effect of a self-immersed view on pain perception.

Experimental

The participant will exert self-immersed, first-person self-talk following a cue-card while induced with experimental pain.

干预措施: Self-immersed, first-person self-talk. (Behavioral)

The effect of non-view, self-talk on pain perception.

Experimental

The participant will exert self-talk following a cue-card while induced with experimental pain.

干预措施: Distraction (Behavioral)

Pain perception in induced, experimental pain.

No Intervention

Control group. This group will be induced with experimental pain, but will receive no specific task to exert.

结局指标

主要结局

Pain tolerance

时间窗: At the test session, the amount of time in seconds the participant withhold their hand in a cold water bath while engaging in self-talk will be measured. Data will be collected until study completion, approximately 1 year.

The amount of time in seconds the participant can withhold their hand in the cold pressor test.

Pain intensity

时间窗: The participant will be asked to estimate their pain from the hand (immersed in cold water) on the Numerical Rating Scale at the experimental test session. Data will be collected until study completion, approximately 1 year.

The estimated experimental pain intensity on the Numerical Rating Scale. Minimum value of the Numerical Rating Scale is 0, which is equivalent with no pain. Maximum value of the Numerical Rating Scale is 10 which is equivalent of worst imaginable pain.

Pain-related fear

时间窗: The participant will be asked to estimate their pain-related fear accompanying the pain they felt when the hand was immersed in cold water on the Numerical Rating Scale. Data will be collected until study completion, approximately 1 year.

The estimated pain-related fear on the Numerical Rating Scale. Minimum value 0 and maximum value 10.

Change in blood pressure before and during pain induction.

时间窗: The blood-pressure will be measured at the beginning of each test session and during the pain induction during each condition. Data will be collected until study completion, approximately 1 year..

The difference score between the blood pressure before the pain induction and the blood pressure during the pain induction will be compared between the different groups. For example, the difference score between the blood pressure in the self-distanced, third-person self-talk condition will be compared to the difference score in the self-immersed, first-person self-talk condition.

次要结局

未报告次要终点

研究者

发起方
Linnaeus University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Helena Gunnarsson

Senior lecturer

Linnaeus University

研究点 (1)

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