An label comparative clinical study to evaluate the effect of vidaryadhigana kashaya capsule with and without daiva vyapasrya chikitsa in smritibhramsa w s r to senile dementia
试验速览
- 阶段
- Phase 3 4
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- To find out the effect of capsule Vidaryadhi gana kashaya in senile dementia by improving cognitive function, memory,executive function like decision making.
研究概览
简要总结
Ageing is an inevitable physiological process that ultimately leads to death. It is divided into two types Kalaja and Akalaja 1. As the time progresses from birth to death age related diseases arise. Old age is an incurable disease which sums the image of frail wrinkled skin, dribbling of saliva, uncontrollable bowel and bladder,declined memory, intellect, thought process, change in behaviour without altered consciousness. Dementia is an acquired deterioration in cognitive ability that impairs successful performance of activities of daily living. Memory is the most common cognitive ability lost with dementia. Recent study showed 10% of the individual above age group of 70 and 20- 40% of individual above 85 years have clinically identified memory loss2.It is defined as a global impairment of cognitive function and is progressive and non-reversible. Dementia, after being ruled out by various causes of mental deterioration such as Alzheimer’s, Parkinson’s disease, somatic causes like Cerebrovascular accident, Head trauma, Alcohol induced and Vascular changes. Dementia caused due to old age is explained as Degenerative changes occurring in the brain. Patients lose their abilities to perform day to day activities necessitating assistance from care givers. Despite advancements in the field of medicine, addressing the diseases of old age remains a significant challenge in this century. There are still limitations in curing and treating conditions like Dementia. Hence there is a need for detailed studyin the field for therapeutic aspects of SmritiBhramsha/Senile Dementia. This study is planned to evaluate inducing good / adequate quality of life.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 60.00 Year(s) 至 80.00 Year(s)(—)
- 性别
- All
入选标准
- •Subjects fulfilling DSM-5 Diagnostic criteria and having the symptoms of Na Smarathi (no remembrance) or Ayathava Ardha Smarathi (incomplete remembrance of things).
- •Patients are selected of age group of 60 and above Patients willing to sign informed consent.
排除标准
- •Patient suffering from other systemic illness and other metabolic disorders interfering with the treatment protocol Patients suffering from other psychiatric illness or disorders.
- •Patients suffering from substance abuse.
结局指标
主要结局
To find out the effect of capsule Vidaryadhi gana kashaya in senile dementia by improving cognitive function, memory,executive function like decision making.
时间窗: 28 days
次要结局
- Concern of individual or a knowledgeable informant complaining there is mild decline in cognitive functions like Executive function, Language, Learning and Memory. Without any behavioral disturbances.
研究者
Dr Vedantam vinay vardhan
SDM college of ayurveda kuthpady udupi.
