Effectiveness and harmlessness of oral probiotic strains in the treatment of patients with plaque psoriasis in a double-blind randomized clinical trial.
Phase 3
Recruiting
- Conditions
- Psoriasis.Psoriasis
- Registration Number
- IRCT20130108012065N3
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 44
Inclusion Criteria
All people between 18 and 70 years old
Patients with plaque psoriasis who are treated with topical corticosteroids
Patients with plaque psoriasis who have not received treatment with systemic drugs or at least three months have passed since the discontinuation of systemic drugs for their treatment and have not received astertine.
Exclusion Criteria
pregnancy
People undergoing chemotherapy
People with a history of any skin disease
History of taking antibiotics in the previous 2 weeks or symptoms of bacterial infection
Diagnosis of liver disease with Child-Pugh C index
Renal failure with serum creatinine >1.5 mg/dl
People with a history of receiving acitretin
History of any type of surgery in the last 3 months
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method PASI Score. Timepoint: The first visit and 4 weeks later and 12 weeks after the first visit. Method of measurement: PASI score.;Patient satisfaction rate. Timepoint: It will be used after 2-3 weeks from the start of the medication until the end of the treatment process. Method of measurement: Standard questionnaire (treatment satisfaction questionnaire for Medication) TSQM.
- Secondary Outcome Measures
Name Time Method