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Efficacy and safety of underwater endoscopic mucosal resection (UEMR) for nonampullary duodenal adenomatous lesio

Phase 2
Conditions
onampullary duodenal adenomatous lesion
Registration Number
JPRN-UMIN000024309
Lead Sponsor
Chiba University
Brief Summary

The mean size of the lesions was 13.3+-6.0mm. Low-grade dysplasia, high-grade dysplasia, and intramucosal carcinoma were 4, 10, and 5, respectively. The rates of en bloc and R0 resections were 68.4% and 31.6%, respectively. There were no cases of perforation or delayed bleeding. Additionally, there were no cases of residual tumors by pathological assessment via biopsy 3 months after UEMR.

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
18
Inclusion Criteria

Not provided

Exclusion Criteria

Patients evaluated incompetent by doctors in attendance

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The rate of pathological local recurrence at 3 months after underwater endoscopic mucosal resection (UEMR) for nonampullary duodenal adenomatous lesion by biopsy from the scar post UEMR
Secondary Outcome Measures
NameTimeMethod
The rate of morphological local recurrence at 3 months after underwater endoscopic mucosal resection (UEMR) for nonampullary duodenal adenomatous lesion, patients' characteristics (e.g. age, gender), lesions' characteristics (e.g. location, diameter, macroscopic appearance), safety (e.g. complications), and relationship between these and outcomes of other endoscopic therapy
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