The effect of metformin on thyroid nodule
Phase 1
- Conditions
- Thyroid nodule.Nontoxic single thyroid nodule
- Registration Number
- IRCT2016022325895N3
- Lead Sponsor
- Vice chancellor for research, Arak University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 240
Inclusion Criteria
Female sex, benign thyroid nodule with the size of 0.5-3 cm, euthyroid, negative TPO-Ab, TSH between 0.5-2.5 mU/L, lack of chronic disease, lack of drug usage
Exclusion criteria: Chronic usage of any kind of drugs more than three months, thyroid cystic nodules, malignant thyroid nodules
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The changes of thyroid nodule size. Timepoint: The beginning of the study, after three months. Method of measurement: Ultrasonography.
- Secondary Outcome Measures
Name Time Method The changes of serum TSH level. Timepoint: The beginning of the study, the beginning of the second month, the beginning of the third month, the end of the third month. Method of measurement: Blood test.