Determination of the Effect of Different Types of Isolated Dietary Fiber on ad Libitum Food Intake in Healthy Human Subjects
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 123
- 试验地点
- 1
- 主要终点
- Ad libitum intake
研究概览
简要总结
It has been suggested that dietary fibers can affect food intake and satiation. Satiation, or meal termination, can be induced by sensory properties and energy density of fiber-rich food products, but also by the chemical/physical/rheological behavior of the fibers in the stomach and/or intestine. It is not clear which properties are the key regulators of satiation by fiber sources. There are many types of dietary fiber, which have diverse sensory and chemical properties, thus these might have different effects on satiation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 50 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age: 18-50 years
- •BMI: 18-25 kg/m2
- •Healthy: as judged by the participant
排除标准
- •Weight loss or weight gain of more than 5 kg during the last 2 months
- •Using an energy restricted diet during the last 2 months
- •Lack of appetite for any (unknown) reason
- •Having problems with chewing and swallowing
- •Having problems with digestion
- •Restrained eater
- •Hypersensitivity for gluten or other ingredients of chocolate cookies
- •Hypersensitivity for one of the fibers
研究组 & 干预措施
Control
No regular flour replaced
干预措施: cellulose, alginate, guar gum (Dietary Supplement)
5% Cellulose
5% regular flour is replaced by cellulose
干预措施: cellulose, alginate, guar gum (Dietary Supplement)
2.5% Alginate
2.5% regular flour is replaced by Alginate
干预措施: cellulose, alginate, guar gum (Dietary Supplement)
5% Alginate
5% regular flour is replaced by Alginate
干预措施: cellulose, alginate, guar gum (Dietary Supplement)
2.5% Guar gum
2.5% regular flour is replaced by Guar gum
干预措施: cellulose, alginate, guar gum (Dietary Supplement)
1.25% Guar gum
1.25% regular flour is replaced by Guar gum
干预措施: cellulose, alginate, guar gum (Dietary Supplement)
结局指标
主要结局
Ad libitum intake
时间窗: 1 hour and 2 hours
次要结局
- eating rate(1 hour and 2 hours)
