The comparative study of salivary fluoride concentration and fluoride retention after toothbrushing with and without rinsing in 6 years old children.

Phase 1

Completed

• Conditions: Dry tooth brushing with 1500 ppm fluoride toothpaste in 6 year-old children; children; dry brushing; fluoride retention; fluoride toothpaste; salivary fluoride concentration

• Registration Number: TCTR20240403005
• Lead Sponsor: Postgraduate Study and Research Sector

Brief Summary

Brushing with 1500 ppm fluoride toothpaste, either with or without rinse, provided a comparable increase in salivary fluoride concentration of children from 5 minutes onwards, which is in the level that can prevent dental caries formation. While brushing without rinse made more fluoride retention than the other.

Detailed Description

Not available

Study Timeline

• Study Completion: 2023-06-30
• Study Start: 2024-04-03
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 18

Inclusion Criteria

1 Healthy children aged 6-y-o
2 No history of drug allergy
3 Not receiving any medication affecting salivary flowrate
4 Not getting fluoride supplement
5 No oral lesion or retained root
6 Have 18 to 24 teeth and dmft less than 5
7 Have normal salivary flowrate
8 Cooperate in research methodology with Frankl behavior scale 3, 4
9 Parents give their written consent

Exclusion Criteria

1 Children who do not meet the inclusion criteria
2 Unable to participate for full experiment period
3 could not comply with the study protocol
4 Parents withdraw their child from the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
salivary fluoride concentration At baseline, 1, 5, 15, 30, 60, and 90 minutes after brushing ppmF / ion-specific electrode

Secondary Outcome Measures

Name	Time	Method
Fluoride retention before and after brushing percentage of fluoride ingestion / ion-specific electrode