Neuromuscular Electrical Stimulation (NMES) on Knee Osteoarthritis(OA): an Equivalence Randomized Clinical Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Osteoarthritis, Knee
- Sponsor
- Universidade Luterana do Brasil
- Enrollment
- 19
- Primary Endpoint
- Evaluation of the flexibility of the posterior chain muscles
- Status
- Completed
- Last Updated
- 15 years ago
Overview
Brief Summary
Objective: To evaluate the effectiveness of neuromuscular electrical stimulation (NMES) combined with closed kinetic chain (CKC) exercises in patients with knee OA.
Detailed Description
Abstract: Introduction: Osteoarthritis (OA) is a degenerative and debilitating change that affects the synovial joints. Objective: To evaluate the effectiveness of neuromuscular electrical stimulation (NMES) combined with closed kinetic chain (CKC) exercises in patients with knee OA. Methods: Nineteen patients with knee OA were enrolled and randomized into two groups: group I was treated with CKC + NMES, and group II was treated with CKC + NMES placebo. Both groups underwent 20 sessions of mini-squat exercises at 30 degrees of knee flexion that were associated with and interspersed with NMES for 5 minutes at a frequency of 40 hertz (Hz), 10 minutes at 70 Hz and an addition 10 minutes at 150 Hz, for a total of 25 minutes. The data were analyzed using SPSS (Statistical Package for the Social Sciences) version 17.0. Data were expressed as a frequency, mean and standard deviation and were statistically analyzed using a one-way analysis of variance (ANOVA) for repeated measurements followed by Bonferroni's post-hoc test. The investigators also used an unpaired Student's t-test and Kruskal-Wallis and Wilcoxon tests with a level of significance of P \< 0.05.
Investigators
Eligibility Criteria
Inclusion Criteria
- •patients with grade I or grade II knee OA (based on the Kellgren-Lawrence classification;
- •which was diagnosed by a medical traumatologist;
- •radiographic changes that demonstrated a reduced joint space in at least one of the compartments of the knee;
- •subchondral bone sclerosis;
- •consent to participate in the study
Exclusion Criteria
- •patients who had grade III and grade IV knee OA (based on the Kellgren-Lawrence classification);
- •who were involved in another rehabilitation program outside the center;
- •who presented with clinical symptoms that would prevent them from participating in the exercises;
- •who had heart disease;
- •cardiac pacemakers;
- •periarticular metal implants;
- •who experienced changes in sensitivity;
- •who had a previous history of knee injury (meniscus, ligaments, sprains);
- •who had uncontrolled diabetes;
- •neurological disorders with cognitive impairments;
Outcomes
Primary Outcomes
Evaluation of the flexibility of the posterior chain muscles
Time Frame: 6 months
We only observed a significant improvement in the flexibility of the posterior muscle chain for the CKC + NMES group during the initial evaluation compared to the partial evaluation (p=0.012), the partial evaluation compared to the final evaluation (p=0.035) and the initial evaluation compared to the final evaluation (p=0.008). Regarding the scale that was used to classify the level of flexibility, 10% of the subjects in the CKC + NMES group were initially classified as good/excellent. At the end of the protocol, 60% of the subjects were classified as good/excellent (p=0.015)
Secondary Outcomes
- Evaluation of hamstring and quadriceps muscle strength(6 months)