Causal Relationship Between Dry Eye and Accommodative Spasm
- Conditions
- Dry Eye
- Interventions
- Device: presbyopia glasses
- Registration Number
- NCT05120401
- Lead Sponsor
- Far Eastern Memorial Hospital
- Brief Summary
To investigate the causal relationship of Sicca dry eye patients with presbyopic refractive error and accommodative spasm.
- Detailed Description
Dry eye is a disease of the ocular surface. Severe dry eye produce symptom of discomfort in and around the eye that drastically affect life quality of the patient. OSDI index is retrieve from a questionnaire specific for these dry eye symptoms, it is an internationally accepted level to reveal the severity of Dry eye disease. One part of the symptom is pain and soreness around the eye. Hyperalgesia is an increase response to a stressful/ noxious stimulus whereas allodynia is a painful response to a normally innocuous stimulus. Our hypothesis state that Sicca Dry eye upregulated inflammatory cytokine in the eye has pre-sensitized the nociceptor nerve fiber in the cornea and orbit, therefore the normally innocuous effort of accommodation and ciliary muscle contraction produce intolerable retro-orbital eye pain, which drives the patient to seek medical attention, on presentations these patient show an elevated OSDI and Pain Index (PI).
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 200
- dry eye
- under 20 year old
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description dry eye with presbyopia presbyopia glasses dry eye with presbyopia , Intervention : glasses prescrubed dry eye with presbyopia without glasses use presbyopia glasses no glasses use
- Primary Outcome Measures
Name Time Method Improve of dry eye / OSDI 30 days OSDI improve
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Far Eastern Memorial Hospital
🇨🇳New Taipei City, Taiwan