Investigating the effect of ??Ethanol- Enoxaparin lock in preventing catheter-related infections

Phase 2

Recruiting

• Conditions: Condition 1: Central-line-associated bloodstream infection. Condition 2: Catheter-related thrombosis.; Infection due to central venous catheter; Other specified complications of cardiac and vascular prosthetic devices, implants and grafts; T80.21; T82.8

• Registration Number: IRCT20220618055207N2
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 27 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 402

Inclusion Criteria

Age = 18
Hematologic malignancy or hematopoietic stem cell transplantation
Recent insertion of the catheter (within the last 48 hours) in aseptic conditions of the operating room, and confirmation of its placement through radiography or radioscopy
Informed consent from the patient or their legal guardian

Exclusion Criteria

History of any allergy/sensitivity/intolerance to Ethanol or Enoxaparin
Pregnancy or breastfeeding
History of alcohol abuse
History of thrombocytopenia caused by heparin (HIT) or having an active hypocoagulable state
Evidence of catheter site infection
Evidence of active systemic infection (fever, chills, positive culture and leukocytosis) or documented bacteremia within 24 hours before catheter placement
Receiving antibiotic treatment
Patients in need of dialysis modalities
Cirrhosis of the liver
Having a history or documented active seizure disorder
Patients whose catheters are placed in emergency situations
Patients in critical conditions (those who need continuous infusion of fluid/medicine through both lumens)

Study & Design

• Study Type: interventional
• Study Design: Not specified