Aneuploidy Rate Impact in Oocyte From Egg Donation Cycle With Different Stimulation Protocol: Recombinant FSH vs Human FSH
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Aneuploidy Rate
- Sponsor
- IVI Madrid
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- Aneuploidy Rate
- Status
- Terminated
- Last Updated
- 10 years ago
Overview
Brief Summary
Several stimulation protocols have been used in in vitro fertilization (IVF) in a cycle of egg donation; recombinant FSH and human FSH are included. The effect of each kind of hormone on aneuploidy rate it is unknown. If there was an increase on aneuploidy rate of one of these stimulation protocols, there will be a negative effect on the successful rates in the egg donation cycles. The aim of this study is to observe if there is a different in aneuploidy rate and morphological oocyte parameters between different stimulation protocols.
Investigators
Juan A Garcia-Velasco
PhD, MD
IVI Madrid
Eligibility Criteria
Inclusion Criteria
- •Egg donation cycles with more than 8MII in oocyte retrieval day
Exclusion Criteria
- •Male factor
- •Uterine malformations
- •genetic alterations
Outcomes
Primary Outcomes
Aneuploidy Rate
Time Frame: 2011 January
Analysis of all nuclei fixed
Secondary Outcomes
- Outcome rates (implantation, pregnancy and miscarriage rate)(2011 April)
- Oocyte morphology(2011 january)