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Clinical Trials/NCT01164943
NCT01164943
Terminated
Not Applicable

Aneuploidy Rate Impact in Oocyte From Egg Donation Cycle With Different Stimulation Protocol: Recombinant FSH vs Human FSH

IVI Madrid1 site in 1 country80 target enrollmentJuly 2010
ConditionsAneuploidy Rate

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Aneuploidy Rate
Sponsor
IVI Madrid
Enrollment
80
Locations
1
Primary Endpoint
Aneuploidy Rate
Status
Terminated
Last Updated
10 years ago

Overview

Brief Summary

Several stimulation protocols have been used in in vitro fertilization (IVF) in a cycle of egg donation; recombinant FSH and human FSH are included. The effect of each kind of hormone on aneuploidy rate it is unknown. If there was an increase on aneuploidy rate of one of these stimulation protocols, there will be a negative effect on the successful rates in the egg donation cycles. The aim of this study is to observe if there is a different in aneuploidy rate and morphological oocyte parameters between different stimulation protocols.

Registry
clinicaltrials.gov
Start Date
July 2010
End Date
December 2012
Last Updated
10 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
IVI Madrid
Responsible Party
Principal Investigator
Principal Investigator

Juan A Garcia-Velasco

PhD, MD

IVI Madrid

Eligibility Criteria

Inclusion Criteria

  • Egg donation cycles with more than 8MII in oocyte retrieval day

Exclusion Criteria

  • Male factor
  • Uterine malformations
  • genetic alterations

Outcomes

Primary Outcomes

Aneuploidy Rate

Time Frame: 2011 January

Analysis of all nuclei fixed

Secondary Outcomes

  • Outcome rates (implantation, pregnancy and miscarriage rate)(2011 April)
  • Oocyte morphology(2011 january)

Study Sites (1)

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