Morning to evening ratio in total dose of twice-daily biphasic insulin analog in achieving glucose control in patients with poorly controlled type 2 diabetes

Not Applicable

Terminated

• Conditions: Endocrine, nutritional and metabolic disease

• Registration Number: KCT0000568
• Lead Sponsor: Yonsei University Health System, Severance Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 11 March 2019

Recruitment & Eligibility

• Status: Terminated
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1) Subjects aged more than 20 years old
2) Subjects with type 2 diabetes who were on sulphonylurea for glucose control
i) more than 7.5% A1c level at the time of enrollment
3) Subjects who have willingness to keep the protocl
4) Subjects who consent in written form

Exclusion Criteria

1) Cancer patients who currently on or will be scheduled for chemotherapy or radition therapy within 6 months.
2) Subjects with renal failure who currently on or will be scheduled for hemodialyisis therapy within 6 months
3) Subjects with heart failure (more than NYHA stage 3)
Subjects with liver failure (more than Child-Pugh class B)
4) Gestational diabetes, type 1 diabetes and secondary yperglycemia, such as iatrogenic,inflammatory, or endocrine disorders, and liver cirrhosis.
5) Subjects who do not consent the study

Study & Design

• Study Type: Observational Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pattern of changes in spilt dose of total insulin

Secondary Outcome Measures

Name	Time	Method
Changes of HbA1c