Efficacy of Mixed Reality Motor-Cognitive Exercise Interventions on Cognitive and Physical Functions Among Older Adults
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
研究概览
简要总结
This study aimed to compare the effects of an 8-week mixed reality motor-cognitive training (MR-MCT) intervention to an active comparison group on cognitive and physical functioning and age-related biomarkers in older adults aged 60 years or older with cognitive frailty.
详细描述
A two-arm randomized controlled trial was conducted with ≥30 older adults aged 60+ with cognitive frailty during the winter semester of 2026.
This study aimed to enroll a minimum of 30 community-dwelling older adults with cognitive frailty to participate in this study, which took place in School of Kinesiology facilities from February 16 to May 8, 2026.
Participants in the intervention group engaged in an 8-week MR-MCT intervention, consisting of two 45-minute MR-MCT sessions per week, starting from March 13 through May 2.
Participants in the active comparison group engaged in an 8-week Tai Chi and multicomponent exercise group sessions, one 45-minute Tai Chi group session, and one 45-minute multicomponent exercise group session each week, starting from March 10 through April 30.
The study outcomes were assessed at baseline and post-intervention assessment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
盲法说明
Evaluators were blinded to arm/group allocation. In other words, evaluators did not know in which group/arm participants were.
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age 60 years or older;
- •self-determined to be able to exercise safely;
- •voluntarily completing all study activities;
- •voluntarily signing the informed consent;
- •willing to be randomized to either MR-MCT intervention group or the active comparison group; and
- •meeting one of the following criteria:
- •having subjective cognitive decline (self-report) or MCI: indicated by a Mini-Cog TM score of <4 to increase sensitivity of MCI;
- •exhibiting pre-physical frailty or physical frailty, as indicated by a score of 1-2 (pre-frailty) or 3-5 (frailty) on the 5-item FRAIL scale.
- •low physical activity, defined as less than 600 Metabolic Equivalent of Task (MET)-min/week and fewer than two 10-min sessions of strengthening exercises per week in the past three months on the International Physical Activity Questionnaire -Short Form (IPAQ-SF) with Muscle Strength.
排除标准
- •recent history of myocardial infarction, stroke, or physical limitations as identified on the Physical Activity Readiness Questionnaire (PARQ);
- •Severe obesity: Body mass index (BMI) of 40 or higher; or
- •concurrent participation in another intervention study.
研究者
Weiyun Chen
Associate Professor
University of Michigan