CTRI/2024/04/066048尚未招募4 期
Analgesic efficacy of Dexmedetomidine versus Magnesium Sulfate as an adjuvant to Ropivacaine in Ilioinguinal and Iliohypogastric nerve block for unilateral Open Inguinal Hernia Repair under Spinal Anaesthesia: A Randomized Controlled Trial
Dr Bodigandla Reddi Gireesh1 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2024年4月30日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Time to the requirement of first dose of rescue analgesic
研究概览
简要总结
Inguinal hernia repair is usually done under spinal anaesthesia. Regional anaesthesia technique (IIIH block) provides pain relief for longer duration after the surgery, which will lead to early discharge from the hospital and also decreases the risk of developing chronic post-surgical herniorrhaphy in the long term. So, we want to compare the effect of adding dexmedetomidine or magnesium sulfate to this block to provide better and longer duration of pain relief without the side effects of usual pain medications like opioids.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients posted for unilateral inguinal hernia repair under spinal anaesthesia,
- •Age 18-60 years,
- •American Society of Anesthesiologists (ASA) physical status I-III.
排除标准
- •Contraindication to peripheral nerve blocks
- •Pre-existing neuropathy
- •Coagulopathy
- •BMI ≥ 35 kg/m²
- •Chronic use of analgesics
- •Patients with cognitive impairment.
结局指标
主要结局
Time to the requirement of first dose of rescue analgesic
时间窗: in minutes
次要结局
- 1. Total opioid consumption (‘morphine equivalents in milligrams’) in postoperative period,(2. Intraoperative- Heart Rate (HR), Systolic Blood Pressure (SBP), Diastolic Blood Pressure (DBP), Mean Arterial Pressure (MAP) and, SpO2 every 5 minutes for the first 30 minutes of surgery and then every 15 minutes till the end of surgery,)
研究者
Dr Bodigandla Reddi Gireesh
Kalinga Institute of Medical Sciences
研究点 (1)
Loading locations...
相似试验
招募中
不适用
Comparison of Postoperative Analgesic Effects of Quadro-iliac Plane Block and Transversus Abdominis Plane Blocks in Inguinal Hernia SurgeryNCT07442188Ankara Etlik City Hospital60
尚未招募
2/3 期
This study aimed to compare effect of iv dexmedetomidine and midazolam for sedation during surgeries undergoing supraclavicular block.CTRI/2024/09/073621Bj medical college100
已完成
不适用
A Study to compare two doses of Dexmedetomidine as an additive in injection Ropivacaine for an analgesic abdominal block for hernia surgeryCTRI/2024/11/077503NKP Salve Institute of Medical Sciences and Research Centre and Lata Mangeshkar Hospital68
尚未招募
4 期
Sedation with two different drugs and postoperative recovery in patients undergoing Endoscopic Retrograde CholangiopancreatographyCTRI/2024/06/069669M D M Hospital Dr S N Medical College Jodhpur100
尚未招募
不适用
A clinical trail to study the effect of intrathecal Dexmeditomidine with Magnesium sulphate as an additional adjuvant to intrathecal Morphine and Bupivacaine combination for post operative analgesia in patients undergoing major abdominal surgeries.CTRI/2024/03/06390660