Comparision Between Conventional Therapy And High Flow Nasal Oxygenatio
Not Applicable
- Conditions
- Health Condition 1: J441- Chronic obstructive pulmonary disease with (acute) exacerbation
- Registration Number
- CTRI/2021/09/036515
- Lead Sponsor
- Deparment Of Anesthesiology And Critical Care
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Informed consent from patient or his legal guardian
2.Age between 40 years to 90 years.
3.Known case of COAD
Exclusion Criteria
1.Coexisting hypoxemia (PaO2/FiO2 <200)
2.Unconscious patients
3.Those unable to maintain airway because of any neurological reasons
4.Hemodynamically unstable patients
5.Patients with nasal condition affecting the ability to use high frequency nasal cannula-nasal blockage, perforated nasal septum, recent epistaxis etc
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare changes in partial pressures of Carbon Dioxide between Conventional oxygen therapy (COT)and High Flow Nasal Oxygenation (HFNO) groups.Timepoint: To compare changes in partial pressures of Carbon Dioxide between Conventional oxygen therapy (COT)and High Flow Nasal Oxygenation (HFNO) group at base line ,1 hour and 2 hour
- Secondary Outcome Measures
Name Time Method Compare the changes in <br/ ><br>i.Partial pressure of oxygen, <br/ ><br>ii.Incidence of need for mechanical ventilation, <br/ ><br>iii.Time to discharge from ICU, <br/ ><br>iv.Time to discharge from hospital, <br/ ><br>v.Rate of readmission and time to readmission <br/ ><br>Timepoint: at zero hour .1 hour and 2 hours