CTRI/2020/02/023300已完成不适用
A COMPARATIVE STUDY OF POST OPERATIVE ANALGESIC EFFICACY OF BILATERAL SUPERFICIAL CERVICAL PLEXUS BLOCK WITH 0.25% ROPIVACAINE VERSUS 0.25% ROPIVACAINE WITH DEXMEDETOMIDINE 0.5 mcg/kg FOR THYROIDECTOMY UNDER GENERAL ANAESTHESIA
JLN MEDICAL COLLEGE AJMER1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2020年2月15日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Duration of post operative analgesia
研究概览
简要总结
The aim of our study is to compare ropivacaine with or without dexmedetomidine in thyroid surgeries under general anaesthesia with respect to:
Primary outcome: Duration of analgesia
Secondary outcome:
1. Total consumption of analgesic in 24h
-
Post-operative nausea and vomiting
-
Adverse effects like hematoma,intravascular injections, local anaesthetic toxicity, bradycardia, hypotensionand sedation
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 16.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients undergoing thyroid surgery under general anaesthesia Patient age between 16 – 60 years ASA (American Society of Anaesthesiologists) physical status I and II.
排除标准
- •Age < 16 and > 60 years ASA physical status III, IV, V and VI.
- •Patients not willing to participate in the study Patient with a known history of sensitivity and contraindications to drugs used Patients with a known history of chronic analgesic consumption Patients with a known history of psychiatric illness Patients non-euthyroid at the time of surgery.
- •Patients with known coagulopathy Infection at the site of block Patients with substernal goitre Patients with stridor or respiratory compromise Patients with thyroid malignancy requiring block dissection Patients having advanced heart block Patients with severe ventricular dysfunction, and/or hypovolemia Patients with co-mobidities like diabetes mellitus or chronic hypertension.
结局指标
主要结局
Duration of post operative analgesia
时间窗: Duration of study is around 1 year
次要结局
- 1. Total consumption of analgesic in 24h(2. Post-operative nausea and vomiting)
研究者
研究点 (1)
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