DRKS00033718招募中不适用
Analysis of the gut microbiome of patients with rare monogenic metabolic diseases - MicroMeDi
niversitätsklinikum Heidelberg0 个研究点目标入组 500 人开始时间: 2024年2月26日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 500
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 3 Years 至 one（—）
- 性别
- All
入选标准
- •Children and adults
- •- with confirmed diagnosis of a rare monogenic metabolic disease
- •- who are heterozygous carriers of variants in a gene leading to a rare metabolic disease
- •- who do not carry variants in a gene responsible for a rare monogenic metabolic disease. These serve as healthy controls (age and region matched to the patients)
排除标准
- •- Active or recent illegal substance or alcohol abuse or dependence within the past year.
- •- History of other significant medical disorders apart from rare monogenic metabolic disease (e.g. leukaemia, diabetes mellitus, renal failure…)
- •- Use of antibiotics or probiotics within six months prior to sampling
- •- Individuals having had digestive surgery, are on restrictive diets, or are pregnant
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