Endoscopic Assessment and Prediction of Microbiome-modifying Interventions
试验速览
- 阶段
- 不适用
- 入组人数
- 45
- 试验地点
- 2
- 主要终点
- Microbiome composition
研究概览
简要总结
The investigators would like to examine the extent of gut microbiome rehabilitation in healthy people after the consumption of antibiotics.
Outcomes of probiotic treatment versus bacteriotherapy will be compared.
详细描述
The investigators would like to examine the extent of rehabilitation of the composition and functioning of the intestinal bacteria in healthy people after the consumption of antibiotics.
Since the digestive mocus enables the connection between the host and the bacteria that live within it, the investigators would like to characterize the microbiome in the different areas along the digestive system - before antibiotic treatment and after rehabilitation by probiotic treatment versus bacteriotherapy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy volunteers
- •Age: 18 years and up
- •Gender: women and men
排除标准
- •Pregnancy
- •Age under 18 years
- •antibiotic treatment 3 months prior to enrollment
- •Viral Hepatitis
- •HIV positive
研究组 & 干预措施
Probiotic microbiome rehabilitation
Probiotic treatment after antibiotic treatment.
干预措施: Probiotic treatment (Dietary Supplement)
No intervention
No intervention after antibiotic treatment.
Bacteriotherapy microbiome rehabilitation
Bacteriotherapy after antibiotic treatment.
干预措施: Bacteriotherapy (Biological)
结局指标
主要结局
Microbiome composition
时间窗: 1 year
stool samples
次要结局
- Microbiome composition(1 month)