Non Substitutive Strategies to Improve Haemophilia Care in Developing Countries. Experience in Ivory Coast.

Not Applicable

Completed

• Conditions: Haemophilia; Developing Countries
• Interventions: Other: Education; Diagnostic Test: Improve biological diagnosis and follow-up of haemophilia; Drug: Implement haemostatic non substitutive care of haemophilia; Other: Implement non haemostatic care of haemophilia

• Registration Number: NCT03054662
• Lead Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Brief Summary

This study aims to make an inventory of the condition and care of patients with haemophilia and carriers for haemophilia in Ivory Coast and to promote the use non substitutive strategies that are not costly and available in Ivory Coast, to improve the management of haemophilia in this country. The purpose of this project is to evaluate the extent to which the active promotion of these various measures will improve the care of patients with haemophilia and carriers in Ivory Coast.

Detailed Description

1. Establish a baseline of the condition of haemophilia in Ivory Coast (number of patients, demographics, reassessment of diagnosis, joint status...).(year 1)

2. Develop tools to assess the intervention (eg transcultural validation of QoL questionnaires, develop booklets to record bleedings...). (year 1)

3. Intervention phase that will focus on education of patients and their family, education of caregivers, training of the laboratory to the diagnosis of haemophilia and promotion of non substitutive strategies to improve haemophilia care in Ivory Coast (DDAVP, antifibrinolytics, physiotherapy, dental care,...).

4. Follow-up phase during 2 years.

5. Outcome analysis

Study Timeline

• Study Start: 2017-01-16
• Study First Submitted: 2017-02-13
• Study First Submitted QC: 2017-02-13
• Study First Posted: 2017-02-15
• Primary Completion: 2018-12-31
• Status Verified: 2019-09
• Study Completion: 2019-09-17
• Last Update Submitted: 2019-09-26
• Last Update Posted: 2019-09-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 142

Inclusion Criteria

• Males with severe and moderate haemophilia A and B in Ivory Coast (any age).
• Females over 12 years who are carriers for severe and moderate haemophilia A and B in Ivory Coast.

Exclusion Criteria

subjects not willing to participate.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Carriers for Haemophilia	Education	Carriers for severe and moderate haemophilia A and B in Ivory Coast
Patients with Haemophilia	Implement haemostatic non substitutive care of haemophilia	Male patients with severe and moderate haemophilia A and B in Ivory Coast
Patients with Haemophilia	Implement non haemostatic care of haemophilia	Male patients with severe and moderate haemophilia A and B in Ivory Coast
Patients with Haemophilia	Improve biological diagnosis and follow-up of haemophilia	Male patients with severe and moderate haemophilia A and B in Ivory Coast
Patients with Haemophilia	Education	Male patients with severe and moderate haemophilia A and B in Ivory Coast
Carriers for Haemophilia	Implement haemostatic non substitutive care of haemophilia	Carriers for severe and moderate haemophilia A and B in Ivory Coast
Carriers for Haemophilia	Improve biological diagnosis and follow-up of haemophilia	Carriers for severe and moderate haemophilia A and B in Ivory Coast

Primary Outcome Measures

Name	Time	Method
Improve haemophilia care in Ivory Coast	2 years after intervention	Compare the pain assessment before and after the intervention phase
Improve haemophilia diagnosis of haemophilia in Ivory Coast	3 years	Compare the number of patients with haemophilia between the beginning and the end of the study
Improve knowledge about haemophilia in Ivory Coast	2 years after intervention	Compare the knowledge queestionnaires about haemophilia before and after the intervention phase

Trial Locations

Locations (1)

CHU de Yopougon; 🇨🇮 Abidjan, Côte D'Ivoire